Figure 1. Histopathological features of IgG4-related disease. (a) Dense infiltration of lymphocytes and plasma cells with storiform fibrosis (H&E staining). (b) Abundant infiltration of IgG4-positive plasma cells (IgG4 immunostaining). (c) Obliterative phlebitis (arrow, Elastica van Gienson staining).

From: Immunoglobulin G4-related Disease: A New Systemic Disease Emerging in Japan

Figure 2. Images of autoimmune pancreatitis. (a) Diffuse enlargement of the pancreas (arrow) and multiple low-density areas in the kidney (arrowheads) on enhanced CT. (b) Diffuse, irregular narrowing of the main pancreatic duct on endoscopic retrograde pancreatography.

From: Immunoglobulin G4-related Disease: A New Systemic Disease Emerging in Japan

Figure 3. Histological finding of IgG4-related sclerosing cholangitis showing transmural wall thickening with fibrosis and lymphoplasmacytic infiltration (H&E staining).

From: Immunoglobulin G4-related Disease: A New Systemic Disease Emerging in Japan

Figure 4. Images of IgG4-related sclerosing cholangitis. (a) Stenosis of the hilar (arrow) and lower (arrowhead) bile duct on endoscopic retrograde cholangiopancreatography. (b) Intraductal ultrasonography showing extensively symmetrical wall thickening with a smooth inner and outer margin that is not stenotic on cholangiography (arrows).

From: Immunoglobulin G4-related Disease: A New Systemic Disease Emerging in Japan

Figure 5. MRI of IgG4-related dacryoadenitis showing bilateral swelling of lacrimal glands (arrows) and retrobulbar inflammation (arrowhead).

From: Immunoglobulin G4-related Disease: A New Systemic Disease Emerging in Japan

Figure 6. Enhanced CT of IgG4-related retroperitoneal fibrosis showing a soft tissue mass in the renal pelvis (arrow).

From: Immunoglobulin G4-related Disease: A New Systemic Disease Emerging in Japan

Figure 7. Regimen of oral steroid therapy for IgG4-related disease.

From: Immunoglobulin G4-related Disease: A New Systemic Disease Emerging in Japan

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