Figure 1. Comparisons of the eGFR, pH, CO2, and HCO3- at the time of imeglimin initiation and 3 months after treatment initiation. The venous blood gas test revealed increased pH at the time of imeglimin initiation and 3 months after treatment initiation. At 3 months after treatment initiation, the eGFR, CO2, and HCO3- were not significantly different, but CO2 exhibited a decreasing trend. *p < 0.05. Error bars in bar plots represent standard errors of the mean.
CO2: carbon dioxide; eGFR: estimated glomerular filtration rate; HCO3-: hydrogen carbonate; ns: not significant.
From: Imeglimin in Patients with an Estimated Glomerular Filtration Rate Less than 45 mL/min per 1.73 m2: A Case Series
