Table 1. Clinical Characteristics of the Women in 2019 and 2020.

From: Proportion of Late Pregnant Women with Anxiety Symptom under COVID-19 Pandemic in Japan

Year 2019 2020 p-value
Control COVID-19 pandemic
Total number 311 248
Nulliparous women 195 (63) 168 (68) 0.22
Maternal age
<20 years 7 (2) 4 (2) 0.59
≥35 years 111 (36) 101 (41) 0.11
Table 2. Results of Answers for the Generalized Anxiety Disorder Scale-2 (GAD-2) during Pregnancy in 2019 and 2020.

From: Proportion of Late Pregnant Women with Anxiety Symptom under COVID-19 Pandemic in Japan

Year 2019 2020 p-value OR 95% CI
Control COVID-19 pandemic
Total number 311 248
First trimester 105 (34) 79 (32) 0.63
Second trimester 37 (12)* 65 (26) <0.01 2.63 1.7-4.1
Third trimester 22 (7)* 60 (24) <0.01 4.19 2.5-7.0
Table 3. Clinical Characteristics and Results of Answers for the Generalized Anxiety Disorder Scale-2 (GAD-2) during the Third Trimester of Pregnancy in 2019.

From: Proportion of Late Pregnant Women with Anxiety Symptom under COVID-19 Pandemic in Japan

Result of the GAD-2 Positive Negative p-value
Total 22 289
Nulliparity
 Yes 20 (91) 175 (61)
 No 2 (9) 114 (39) <0.01
Maternal age ≥ 35 years
 Yes 12 (55) 99 (52)
 No 10 (45) 90 (48) 0.06
Table 4. Clinical Characteristics and Results of Answers for the Generalized Anxiety Disorder Scale-2 (GAD-2) during the Third Trimester of Pregnancy in 2010 (COVID-19 Pandemic).

From: Proportion of Late Pregnant Women with Anxiety Symptom under COVID-19 Pandemic in Japan

Result of the GAD-2 Positive Negative p-value
Total 60 188
Nulliparity
 Yes 41 (68) 107 (57)
 No 19 (32) 81 (43) 0.12
Maternal age ≥ 35 years
 Yes 22 (37) 79 (42)
 No 38 (63) 109 (58) 0.46
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