| First author (publication year) | Study name | Country | Population | Number of participants (intervention/control) | Sex | Statin user | Diet in the intervention group | Diet in control group | Difference in SFA intake | Follow-up year | Primary outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Rose et al. (18) (1965) | St. Mary Hosp | UK | Post-MI or angina | 54/26 | n.a. | None | Avoid animal fat with supplementation of olive or corn oil | n.a. | n.a. | 2 | Sudden death or MI |
| Leren (19) (1966) | Oslo Diet Heart | Norway | Post-MI | 206/206 | Male 100% | None | SFA8.5% | n.a. | n.a. | 5 | CHD relapse |
| Research Committee (15) (1968) | MRC | UK | Post-MI | 199/194 | Male 100% | None | 85g soya oil SFA15.3% | No soya oil SFA 39.4% | 24.1% energy | 5 | MI |
| Dayton et al. (20) (1969) | Los Angeles Veterans Administration | USA | Veterans domicile | 424/422 | Male 100% | None | Linoleic acid 38.4% of fat | Linoleic acid 10.0% of fat | n.a. | 8 | Sudden death or definite MI |
| Burr et al. (21) (1989) | DART | UK | Post-MI | 1018/1015 | Male 100% | None | P:S=0.78 SFA18.1% | P:S=0.44 SFA24.3% | 6.2% energy | 2 | MI |
| Frantz et al. (22) (1989) | Minnesota Coronary Survey | USA | Mental hospital or nursing home | 4541/4516 | Female 41.5%, male 48.5% | None | SFA9% | SFA18% | 9.1% energy | 4.5 | MI, sudden death, or death |
| Watts et al. (23) (1992) | STARS | UK | CAG | 26/24 | Male 100% | None | SFA9% | SFA16% | 7.0% energy | 3.25 | CAG change |
| Ramsden et al. (24) (2013) | Sydney Diet Heart Study | Australia | Post-ACS | 221/237 | Male 100% | None | PUFA15.4%, SFA9.3% | PUFA8.4%, SFA13.5% | 4.2% energy | 5 | Death |
| Vijayakumar et al. (25) (2016) | Amrita Institute | India | Stable CAD | 100/100 | Female 6.6%, male 93.4% | all | Sunflower oil | Coconut oil | n.a. | 2 | Anthropometric change, lipid profile |
| First author (publication year) | Study name | Population | Reason of exclusion |
|---|---|---|---|
| Turpeinen et al.(30) (1979) | Finnish Mental Hospital Study (Men) | Patients in mental hospital | Non-randomized study |
| Cross-over design without evaluation of carry-over effect | |||
| Most subjects (63.6%) participated in single arm only (not crossed-over) | |||
| Miettinen et al.(31) (1983) | Finnish Mental Hospital Study (Women) | Patients in mental hospital | Non-randomized study |
| Cross-over design without evaluation of carry-over effect | |||
| Most subjects (79.4%) participated in single arm only (not crossed-over) | |||
| Black et al.(32) (1994) | n.a. | Previous skin cancer | Total fat reduction intervention but not SFA |
| No data for CVD or death | |||
| Houtsmuller et al.(33), (34), (35) (1980) | n.a. | Diabetes | Unknown definition of cardiac ischemia |
| Glucose improvement only in women | |||
| Ley et al.(36) (2004) | n.a. | Prediabetes | Total fat reduction intervention but not SFA |
| No data for CVD or death | |||
| Moy et al.(37) (2001) | n.a. | Healthy siblings with a family history of CHD | No data for CVD or death |
| Howard et al.(38) (2006) | Women’s Health Initiative | Postmenopausal women | Total fat reduction intervention but not SFA |
