| Types of CCs | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total sample | Healthy | Single CC | Multiple CCs | HT | DM | DL | HT and DM | HT and DL | DM and DL | HT and DM and DL | |
| (n = 59,703) | (n = 18,654) | (n = 22,404) | (n = 18,645) | (n = 10,566) | (n = 638) | (n = 11,200) | (n = 1,530) | (n = 13,010) | (n = 937) | (n = 3,168) | |
| Sex, n (%) | |||||||||||
| Men | 24,379 (40.8) | 5,606 (30.1) | 9,883 (44.1) | 8,890 (47.7) | 5,341 (50.5) | 382 (59.9) | 4,160 (37.1) | 1,000 (65.4) | 5,723 (44) | 477 (50.9) | 1,690 (53.3) |
| Women | 35,324 (59.2) | 13,048 (69.9) | 12,521 (55.9) | 9,755 (52.3) | 5,225 (49.5) | 256 (40.1) | 7,040 (62.9) | 530 (34.6) | 7,287 (56) | 460 (49.1) | 1,478 (46.7) |
| Age, y | 58.6 (16.1) | 47.4 (15.8) | 61.0 (14.5) | 66.8 (11.2) | 66.3 (12.6) | 67.1 (11.1) | 55.7 (14.4) | 70.3 (9.7) | 66.2 (11.6) | 64.5 (11.4) | 68.3 (9.8) |
| Age category, n (%) | |||||||||||
| <65 y | 34,365 (57.6) | 15,357 (82.3) | 12,155 (54.3) | 6,853 (36.8) | 4,152 (39.3) | 205 (32.1) | 7,798 (69.6) | 368 (24.1) | 5,078 (39.0) | 401 (42.8) | 1,006 (31.8) |
| ≥65 y | 25,338 (42.4) | 3,297 (17.7) | 10,249 (45.7) | 11,792 (63.2) | 6,414 (60.7) | 433 (67.9) | 3,402 (30.4) | 1,162 (75.9) | 7,932 (61.0) | 536 (57.2) | 2,162 (68.2) |
| Systolic BP, mmHg | 131 (19.1) | 116.3 (11.8) | 132.4 (17.8) | 143.8 (16.3) | 144.9 (15.5) | 125 (10.1) | 121.1 (11.1) | 145.9 (16.7) | 144.7 (15.8) | 124.9 (9.7) | 144.8 (16.3) |
| Diastolic BP, mmHg | 78.8 (11.3) | 72.9 (8.4) | 79.8 (10.9) | 83.6 (11.7) | 84.9 (11.4) | 73.8 (8.2) | 75.4 (8.0) | 80.7 (11.7) | 85.1 (11.5) | 75.1 (8.0) | 81.6 (11.9) |
| TC, mg/dL | 203.1 (35.3) | 188.5 (25.6) | 209.4 (35.7) | 210.1 (38.6) | 192.4 (25.5) | 186.2 (26.0) | 226.7 (35.9) | 185.4 (25.7) | 215.2 (38) | 210.7 (41.1) | 201.2 (39.2) |
| TG, mg/dL | 136.6 (97.6) | 85.3 (34.8) | 138.8 (94.4) | 181.1 (116) | 98.2 (34.8) | 96.2 (34.2) | 173.7 (113.4) | 105.8 (34.9) | 182.4 (115.6) | 194 (124.8) | 203.5 (123.8) |
| HDL-C, mg/dL | 61.8 (16.3) | 67.7 (15.0) | 61.6 (16.2) | 56.2 (15.6) | 64.6 (15.8) | 60.6 (14.9) | 58.9 (16.1) | 59.9 (14.6) | 56.8 (15.7) | 54.0 (16) | 52.4 (14.7) |
| LDL-C, mg/dL | 118.4 (31.0) | 104.9 (20.6) | 124.3 (31.8) | 125 (34.2) | 107.2 (20.8) | 105 (21.2) | 141.4 (31.5) | 103.3 (21.7) | 129.3 (34.1) | 125.8 (34.9) | 117.6 (34.1) |
| Plasma glucose, mg/dL | 105.3 (31.7) | 95.3 (15.1) | 101.8 (22.3) | 118.5 (44.8) | 102.6 (18.6) | 152.3 (68.9) | 98.5 (16.2) | 151.1 (62.6) | 104 (19.0) | 154.9 (75.9) | 153.5 (62.7) |
| HbA1c, % | 5.7 (0.7) | 5.4 (0.3) | 5.6 (0.5) | 6.2 (1.0) | 5.6 (0.4) | 7.1 (1.1) | 5.6 (0.3) | 7.1 (1.1) | 5.7 (0.3) | 7.4 (1.4) | 7.2 (1.1) |
| non-HDL, mg/dL | 141.3 (35.0) | 120.8 (22.5) | 147.8 (34.4) | 154 (36.8) | 127.8 (22.1) | 125.6 (22.5) | 167.8 (32.8) | 125.5 (22.7) | 158.4 (36.1) | 156.7 (39.4) | 148.8 (37.6) |
| Medication status | |||||||||||
| Taking drugs, n (%) | 20,706 (34.7) | 0 (0.0) | 7,944 (35.5) | 12,762 (68.4) | 5,536 (52.4) | 371 (58.2) | 2,037 (18.2) | 1,242 (81.2) | 8,287 (63.7) | 607 (64.8) | 2,626 (82.9) |
| Not taking drugs, n (%) | 38,772 (64.9) | 18,654 (100) | 14,440 (64.5) | 5,678 (30.5) | 5,030 (47.6) | 250 (39.2) | 9,160 (81.8) | 243 (15.9) | 4,712 (36.2) | 295 (31.5) | 428 (13.5) |
| Missing, n (%) | 225 (0.4) | 0 (0.0) | 20 (0.1) | 205 (1.1) | 0 (0.0) | 17 (2.7) | 3 (0.0) | 45 (2.9) | 11 (0.1) | 35 (3.7) | 114 (3.6) |
| Differences in steps/d | ||||||
|---|---|---|---|---|---|---|
| Healthy | With single CC | With multiple CCs | Healthy vs single CC | Single CC vs multiple CCs | Healthy vs multiple CCs | |
| Total sample | 6,801 (6,740-6,862) | 6,662 (6,611-6,712) | 6,321 (6,263-6,378) | -139 (−219 to −59) | -341 (−416 to −265) | -480 (−569 to −391) |
| Stratified by sex and age | ||||||
| Men aged <65 y | 8,292 (8,152-8,431) | 7,703 (7,585-7,821) | 6,968 (6,820-7,116) | −588 (−772 to −404) | −735 (−923 to −547) | −1,324 (−1,535 to −1,113) |
| Women aged <65 y | 7,167 (7,096-7,238) | 6,772 (6,685-6,860) | 6,504 (6,372-6,636) | −395 (−512 to −277) | −268 (−421 to −116) | −663 (−820 to −506) |
| Men aged 65 y | 6,454 (6,253-6,655) | 6,164 (6,052-6,275) | 5,806 (5,702-5,910) | −290 (−520 to −61) | −358 (−511 to −206) | −648 (−875 to −422) |
| Women aged 65 y | 5,385 (5,240-5,530) | 5,259 (5,176-5,343) | 5,102 (5,024-5,180) | −126 (−293 to 42) | −158 (−272 to −43) | −283 (−449 to −118) |
