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Table 1. Descriptive Statistics of the Analysis Set Population.

From: Regional Differences and Similarities in Diabetes Care in Japan: Insights from the J-DOME Registry

Statistics Item/Category/Region Statistics
By medical institution unit
　Number of institutions (n) 116
　Number of patients registered per institution (n)
　　Mean (SD) 25.3 (29.8)
　　Median [IQR] 15.5 [7.0-30.0]
　　Range (min-max) 1-150
　Specialist institutions/Non-specialist institutions (n) 45/71
　Region (n)
　　Hokkaido and Tohoku 11
　　North Kanto 13
　　South Kanto 32
　　Chubu 18
　　Kinki 11
　　Chugoku and Shikoku 19
　　Kyushu and Okinawa 12
By diabetes patient unit
　Number of patients (n) 2,938
　Gender (male/female) 1,772/1,166
　Age (years)
　　Mean (SD) 69.2 (11.9)
　　Median [IQR] 71.0 [62.0-78.0]
　　Range 18-99
　Specialist institutions/Non-specialist institutions (n) 1,567/1,371
　Region (n)
　　Hokkaido and Tohoku 119
　　North Kanto 483
　　South Kanto 1138
　　Chubu 231
　　Kinki 373
　　Chugoku and Shikoku 375
　　Kyushu and Okinawa 219
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Table 2. Regional Aggregation of Mean Clinical Laboratory Values by Medical Institution Unit.

From: Regional Differences and Similarities in Diabetes Care in Japan: Insights from the J-DOME Registry

Region Mean SD Median IQR I2 p Value
HbA1c [NGSP] (%) 0.01% 0.242
　All regions 6.96 0.46 7.0 6.7-7.2
　　Hokkaido and Tohoku 6.53 0.63 6.7 6.1-7.1
　　North Kanto 7.10 0.42 7.1 6.8-7.2
　　South Kanto 7.03 0.35 7.0 6.8-7.3
　　Chubu 6.97 0.41 7.0 6.7-7.1
　　Kinki 7.00 0.55 7.1 6.5-7.4
　　Chugoku and Shikoku 6.92 0.50 7.0 6.6-7.3
　　Kyushu and Okinawa 7.07 0.35 7.1 6.8-7.4
Systolic blood pressure (mmHg) 25.89% 0.216
　All regions 129.7 6.1 130 126-134
　　Hokkaido and Tohoku 130.4 6.4 131 127-134
　　North Kanto 128.1 6.0 129 122-133
　　South Kanto 130.7 4.6 130 128-134
　　Chubu 129.2 6.8 128 125-133
　　Kinki 129.5 6.7 129 125-134
　　Chugoku and Shikoku 131.7 5.4 132 128-135
　　Kyushu and Okinawa 125.7 7.5 124 120-129
Diastolic blood pressure (mmHg) 0.00% 0.682
　All regions 73.0 5.7 73 69-77
　　Hokkaido and Tohoku 76.8 9.8 74 72-81
　　North Kanto 72.5 6.1 72 66-79
　　South Kanto 72.1 4.0 73 69-74
　　Chubu 73.7 4.9 73 72-77
　　Kinki 72.9 6.1 72 68-79
　　Chugoku and Shikoku 73.2 5.4 73 69-77
　　Kyushu and Okinawa 71.7 5.5 70 67-77
LDL cholesterol (mg/dL) 13.00% 0.302
　All regions 105.6 12.5 105 97-111
　　Hokkaido and Tohoku 98.5 12.7 103 91-107
　　North Kanto 104.4 13.9 106 98-115
　　South Kanto 106.2 11.5 105 98-114
　　Chubu 102.7 9.1 104 94-108
　　Kinki 109.1 15.7 108 95-123
　　Chugoku and Shikoku 109.7 13.2 109 103-111
　　Kyushu and Okinawa 105.4 12.4 101 97-113
HDL cholesterol (mg/dL) 0.00% 0.477
　All regions 57.6 6.1 58 54-60
　　Hokkaido and Tohoku 58.1 5.6 58 53-62
　　North Kanto 54.4 5.8 55 53-58
　　South Kanto 57.2 4.6 57 55-59
　　Chubu 59.2 5.8 59 55-63
　　Kinki 58.7 6.8 59 52-63
　　Chugoku and Shikoku 57.6 7.9 58 53-61
　　Kyushu and Okinawa 58.0 7.3 57 54-59
log Triglyceride (mg/dL)* 3.11% 0.682
　All regions 2.11 0.10 146 126-168
　　Hokkaido and Tohoku 2.10 0.16 126 111-181
　　North Kanto 2.12 0.11 148 122-179
　　South Kanto 2.10 0.06 146 130-163
　　Chubu 2.15 0.12 149 128-198
　　Kinki 2.09 0.12 149 122-159
　　Chugoku and Shikoku 2.13 0.09 143 131-176
　　Kyushu and Okinawa 2.11 0.07 152 122-166
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Table 3. Mean Clinical Parameters by Specialist and Non-Specialist Institutions.

From: Regional Differences and Similarities in Diabetes Care in Japan: Insights from the J-DOME Registry

Clinical parameters Mean SD Median IQR p Value
HbA1c [NGSP] (%)
　Non-specialist institutions 6.86 0.46 7.0 6.6-7.1 Ref
　Specialist institutions 7.13 0.41 7.1 6.8-7.3 0.001
Systolic blood pressure (mmHg)
　Non-specialist institutions 130.8 6.6 131 126-135 Ref
　Specialist institutions 128.9 4.7 129 126-131 0.105
Diastolic blood pressure (mmHg)
　Non-specialist institutions 73.5 6.3 73 69-78 Ref
　Specialist institutions 72.2 4.6 73 69-75 0.191
LDL cholesterol (mg/dL)
　Non-specialist institutions 105.2 14.0 106 95-112 Ref
　Specialist institutions 106.2 9.8 105 100-111 0.664
HDL cholesterol (mg/dL)
　Non-specialist institutions 57.8 6.8 58 54-60 Ref
　Specialist institutions 57.2 5.0 57 55-61 0.631
log Triglyceride (mg/dL)*
　Non-specialist institutions 2.11 0.11 136 121-171 Ref
　Specialist institutions 2.12 0.07 152 131-167 0.510
Ophthalmology follow-up rate (%)
　Non-specialist institutions 53.9 33.8 50.0 32.0-88.1 Ref
　Specialist institutions 78.5 19.5 80.5 63.4-100.0 <0.001
Urinary albumin quantification test rate (%)
　Non-specialist institutions 28.8 35.7 0.0 0.0-57.5 Ref
　Specialist institutions 58.1 36.0 70.0 21.6-88.9 <0.001
Urinary albumin quantification test rate among patients without macroproteinuria (%)
　Non-specialist institutions 33.5 39.0 13.9 0.0-73.6 Ref
　Specialist institutions 62.5 35.5 75.3 33.3-92.7 <0.001
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