Figure and Table | Imeglimin in Patients with an Estimated Glomerular Filtration Rate Less than 45 mL/min per 1.73 m　: A Case Series

Table 1. Patient characteristics at baseline.

Sex
Male	10 (71.4%)
Female	4 (28.6%)
Age (years) (Mean ± SD)	67.9 ± 7.1
Duration of diabetes (months) (Mean ± SD)	131 ± 53.7
eGFR (mL/min/1.73m²) (Mean ± SD)	28.7 ± 13.0
Proteinuria (g/gCr) (Mean ± SD)	2.01 ± 1.66
HCO₃^- (mmol/L) (Mean ± SD)	24.0 ± 4.4
HbA1c (%) (Mean ± SD)	7.4 ± 0.9
Dose of imeglimin
500 mg/day	10 (71.4%)
1000 mg/day	3 (21.4%)
2000 mg/day	1 (7.1%)
Switching from other medications	8 (57.1%)
Concomitant medications
SGLT2i	7 (50.0%)
GLP1	5 (35.7%)
DPP4i	4 (28.6%)
SU	2 (14.3%)
α-GI	2 (14.3%)
Insulin	2 (14.3%)
GLP1	1 (7.1%)
TZD	1 (7.1%)

Table 2. Comparison of Parameters at the Initiation of Imeglimin and at 3 Months after the Initiation of Imeglimin.