Figure 1. Temporal changes in HbA1c levels after sacubitril/valsartan initiation. HbA1c levels significantly decreased at 3, 6, and 12 months compared with baseline levels (P values for pairwise comparisons of estimated marginal means with Bonferroni adjustment). Error bars represent 95% confidence intervals.
Figure 2. Subgroup analyses. Patients with diabetes showed a significantly greater decrease in HbA1c levels than those without diabetes. BMI, body mass index; LVEF, left ventricular ejection fraction; SGLT2, sodium-glucose cotransporter-2.