Figure 1. DNA methylation status (GWMS) of the whole-genome in colorectal cancer and EpiLight test.
a. Analysis of the methylation status of the entire genome in colorectal cancer using a bead chip and unsupervised cluster analysis, b. Determination of the methylation status using the EpiLight test (taken from the RIKEN GENESIS website).
CpG: XXX; EGFR: estimated glomerular filtration rate; HMCC: highly methylated colorectal cancer; LMCC: low methylated colorectal cancer.

From: Development of the World’s First In Vitro Cancer Epigenome Diagnostic through Biomarker Research for Personalized Cancer Treatment of RAS-wild-type Colorectal Cancer -Secondary Publication - Secondary Publication

Figure 2. Kaplan-Meier survival curves for PFS by DNA methylation status and primary lesion site.
CI: confidence interval; DNA: deoxy ribonucleic acid; HMCC: highly methylated colorectal cancer; HR: hazard ratio; M: month; PFS: progression-free survival.

From: Development of the World’s First In Vitro Cancer Epigenome Diagnostic through Biomarker Research for Personalized Cancer Treatment of RAS-wild-type Colorectal Cancer -Secondary Publication - Secondary Publication

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