Figure 1. Change in mean pain scores on verbal rating scale (VRS).
VRS scores were determined before and on days 3, 5, and 7 after methadone administration. Numerical rating scale (NRS) scores were converted to VRS scores as follows: NRS 0 = no pain (VRS 0), NRS 1-4 = mild pain (VRS 1), NRS > 4-7 = moderate pain (VRS 2), and NRS > 7-10 = severe pain (VRS 3).

From: The Adequateness of Methadone for Japanese Terminal Cancer Patients Can Be Determined Earlier than 7 Days: A Preliminary Retrospective Study

Figure 2. Change in mean usage counts of rescue drugs.
The usage count of rescue drugs was investigated before methadone administration, and on days 3, 5, and 7 after starting methadone administration. When multiple types of rescue drugs were used, the total usage counts were counted.

From: The Adequateness of Methadone for Japanese Terminal Cancer Patients Can Be Determined Earlier than 7 Days: A Preliminary Retrospective Study

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