Figure 3. Histopathological and biochemical features of a-synuclein deposited in PD and DLB brains. Immunohistochemistry of cortical-type Lewy bodies (large arrows) and Lewy neurites (small arrows) in DLB cortices (A) and brain stem-type Lewy body in the substantia nigra of PD brain (B) labeled by a phosphoserine 129-specific anti-α-synuclein antibody. C: Immunoblot analysis of sarkosyl-insoluble fractions from control (C) and DLB (D) cortices with a phosphoserine 129-specific anti-α-synuclein antibody (C).
From: Molecular Pathogenesis and Disease-modifying Therapies of Alzheimer’s Disease and Related Disorders