Table 1. Completed and Ongoing Clinical Trials Led by JGOG.

From: An Attempt to Develop a New Treatment Strategy for Rare Refractory Gynecological Malignancies: The Japanese Gynecologic Oncology Group

Title JGOG ID Target Disease Identifier
Completed randomized clinical trials Randomized phase III trial of AP (doxorubicin + cisplatin) therapy, DP (docetaxel + cisplatin) therapy, and TC (paclitaxel + carboplatin) therapy as adjuvant chemotherapy for endometrial cancer at a high risk of recurrence JGOG2043 Endometrial Cancer UMIN000000522
Randomized phase III trial of conventional paclitaxel and carboplatin versus dose dense weekly paclitaxel and carboplatin in patients with newly diagnosed stage II-IV Mullerian carcinoma (ovarian epithelial, primary peritoneal, or fallopian tube cancer) JGOG3016 Ovarian Cancer C000000183
Randomized phase III trial of paclitaxel plus carboplatin (TC) therapy versus irinotecan plus cisplatin (CPT-P) therapy as a first line chemotherapy for clear cell carcinoma of the ovary GCIG/JGOG3017 Ovarian Cancer UMIN000000499
A randomized phase II/III trial of intravenous (IV) paclitaxel weekly plus IV carboplatin once every 3 weeks versus IV paclitaxel weekly plus intraperitoneal (IP) carboplatin once every 3 weeks in women with epithelial ovarian, fallopian tube or primary peritoneal cancer GOTIC/JGOG3019 Ovarian Cancer UMIN000003670/NCT01506856
Ongoing trials/studies Adjuvant chemotherapy versus radiotherapy for postoperative cervical cancer; a phase III trial JGOG1082 Cervical Cancer jRCTs041190042
Clinicopathological study on glassy cell carcinoma of the cervix JGOG1086S Cervical Cancer UMIN000050237
A non-randomized confirmatory trial of minimum invasive laparoscopic radical hysterectomy (new-Japanese LRH) for patients with early-stage cervical cancer JGOG1087 Cervical Cancer UMIN000045224
Phase II trial of repeated high dose luteal hormone therapy for intrauterine recurrence following fertility preserving therapy for atypical endometrial hyperplasia or endometrial cancer JGOG2051 Endometrial Cancer jRCT031200256
Phase II study of niraparib in recurrent or persistent rare fraction of gynecologic malignancies with homologous recombination deficiency JGOG2052 Uterine Leiomyosarcoma and Others jRCT2031210264
Phase III trial of stage I ovarian cancer after surgery JGOG3020 Ovarian Cancer jRCTs031180423/NCT04063527
Prospective cohort study of germline variant carriers with BRCA1 or BRCA2 JGOG3024 Ovarian Cancer UMIN000028740/NCT03296826
Assessment of the efficacy and safety of pembrolizumab for ovarian squamous cell carcinoma JGOG3029 Ovarian Cancer jRCT2031220701
An observational study to investigate the safety and efficacy of olaparib combined with bevacizumab therapy after primary chemotherapy plus bevacizumab for Japanese patients with advanced ovarian, fallopian tube, or primary peritoneal cancer JGOG3030 Ovarian Cancer UMIN000047107
An observational study to investigate the safety and efficacy of niraparib for Japanese patients with recurrent ovarian cancer: maintenance therapy for platinum-sensitive recurrent treatment and monotherapy for late-line treatment JGOG3031 Ovarian Cancer UMIN000046970
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