Figure and Table | atients 　ffer 　dio　requency 　blation Therapy for 　arly Breast Cancer as 　cal Therapy (PO-RAFAELO) Study under the Patient-proposed Health Services

Table 1. Overview of Each Technology for the Patient-Proposed Health Services.

Registration No.	Medical technology of patient-offered therapy	Diseases for which a specific medicine is indicated
1.	Combination therapy of intraperitoneal and intravenous paclitaxel and oral S-1	Peritoneal dissemination or advanced gastric cancer
2.	-	-
3.	Oral infigratinib therapy	Advanced solid tumors
4.	Percutaneous radiofrequency ablation of breast cancer	Early-stage breast cancer (limited to breast cancer with a long diameter of 1.5 cm or less)
5.	Molecular targeted therapy based on gene profiling by multiplex gene panel test	Advanced solid tumors that cannot be curatively resected
6.	Intravenous trastuzumab emtansine	Extramammary Paget’s disease
7.	-	-
8.	Intravenous rituximab	Refractory chronic inflammatory demyelinating polyneuropathy
9.	Combination therapy with oral dabrafenib and oral trametinib	Glioma

Table 2. Schedule of Follow-up after RFA in the PO-RAFAELO Study

	Preregistration	Intraoperative/ postoperative	Within 1 week after RFA	Approximately 3 months after radiation completion
Patient characteristics: current and previous medical history	〇
Interview	〇		〇	〇
Visual assessment and palpation	〇	〇		〇
MG	〇
CNB* or VAB	〇			〇
Breast US	〇	〇		〇
Breast MRI and/or CT scan	〇			〇
Chest radiography	〇
Tumor marker evaluation	〇			〇