Table 1. Study Participant Characteristics.

From: Factors Associated with Non-attendance at a Follow-up Visit for Dyslipidemia Identified at Health Checkups: A Retrospective Cohort Study in a Japanese Prefecture

Attended a follow-up visit Did not attend a follow-up visit Total
(n = 6,052) (n = 27,451) (n = 33,503)
Age, median (IQR), year 67 (61-70) 66 (58-69) 66 (59-69)
Sex (female) 3,805 (62.9) 15,909 (58.0) 19,714 (58.8)
BMI, kg/m2
 <25 4,362 (72.1) 20,062 (73.1) 24,424 (72.9)
 25-30 1,465 (24.2) 6,482 (23.6) 7,947 (23.7)
 ≥30 225 (3.7) 907 (3.3) 1,132 (3.4)
Current smoker, yes 810 (13.4) 4,271 (15.6) 5,081 (15.2)
Frequency of alcohol consumption
 Every day 1,140 (18.8) 5,704 (20.8) 6,844 (20.4)
 Occasionally 1,180 (19.5) 5,863 (21.4) 7,043 (21.0)
 Rarely 3,732 (61.7) 15,884 (57.9) 19,616 (58.6)
Symptoms, yes 1,939 (32.0) 7,458 (27.2) 9,397 (28.1)
Health checkup results
 Hypertension 1,738 (28.7) 7,022 (25.6) 8,760 (26.2)
 Hyperglycemia 619 (10.2) 1,427 (5.2) 2,046 (6.1)
 Liver dysfunction 571 (9.4) 1,984 (7.2) 2,555 (7.6)
 Proteinuria 227 (3.8) 501 (1.8) 728 (2.2)
 Glycosuria 200 (3.3) 463 (1.7) 663 (2.0)
Number of dyslipidemias at the health checkup
 1 5,798 (95.7) 26,460 (96.4) 32,253 (96.3)
 2 251 (4.2) 951 (3.5) 1,202 (3.6)
 3 8 (0.1) 40 (0.2) 48 (0.1)
Place of health checkups
 Public facility 4,664 (77.1) 22,230 (81.0) 26,894 (80.3)
 Medical institution 1,388 (22.9) 5,221 (19.0) 6,609 (19.7)
Prior prescriptions within one year before the health checkup
 Antihypertensive 1,041 (17.2) 2,760 (10.1) 3,801 (11.4)
 Antidiabetic 47 (0.8) 125 (0.5) 172 (0.5)
 Antigout 110 (1.8) 277 (1.0) 387 (1.2)
 Antidepressant 171 (2.8) 418 (1.5) 589 (1.8)
Number of months of physician visits in the previous year, median (IQR), month 4 (1-8) 3 (1-6) 3 (1-6)
Result of the health checkup in the previous fiscal year
 Dyslipidemia 3,244 (53.6) 15,779 (57.5) 19,023 (56.8)
 No dyslipidemia 1,220 (20.2) 5,730 (20.9) 6,950 (20.7)
 No health checkup in the previous year 1,588 (26.2) 5,942 (21.7) 7,530 (22.5)
Table 2. Proportion of Attendance at a Follow-Up Physician Visit for Dyslipidemia, by Type and Combination of Dyslipidemia.

From: Factors Associated with Non-attendance at a Follow-up Visit for Dyslipidemia Identified at Health Checkups: A Retrospective Cohort Study in a Japanese Prefecture

Proportion, %
Type of dyslipidemia
LDL-C ≥ 140 mg/dL 17.9 (5,573/31,084)
 LDL-C 140-160 mg/dL 15.7 (2,624/16,723)
 LDL-C 160-180 mg/dL 18.6 (1,655/8,886)
 LDL-C ≥ 180 mg/dL 23.6 (1,294/5,475)
TG ≥ 300 mg/dL 20.7 (574/2,779)
HDL-C ≤ 34 mg/dL 18.3 (172/938)
Combination of dyslipidemia
One type 18.0 (5,793/32,253)
 High LDL-C only 17.9 (5,371/30,079)
 High TG only 20.1 (333/1,654)
 Low HDL-C only 17.1 (89/520)
Two types 20.9 (251/1,202)
 High LDL-C and High TG 21.2 (176/832)
 High LDL-C and Low HDL-C 14.4 (18/125)
 High TG and Low HDL-C 23.3 (57/245)
High LDL-C, High TG, and Low HDL-C 16.7 (8/48)
Table 3. Adjusted Odds Ratios for Attendance at a Follow-Up Physician Visit for Dyslipidemia.

From: Factors Associated with Non-attendance at a Follow-up Visit for Dyslipidemia Identified at Health Checkups: A Retrospective Cohort Study in a Japanese Prefecture

n = 33,503 Unadjusted OR (95% CI) Adjusted OR (95% CI)
Predisposing factors
Age group (years) (ref. 40-49 years old)
 50-59 1.28*** (1.11-1.46) 1.24** (1.09-1.42)
 60-69 1.62*** (1.46-1.79) 1.49*** (1.35-1.63)
 70-74 1.86*** (1.62-2.14) 1.63*** (1.43-1.86)
Male sex 0.81*** (0.76-0.87) 0.79*** (0.74-0.85)
Enabling factors
Place of health checkups (ref. medical institution)
 Public facility 0.79*** (0.73-0.85) 0.89* (0.83-0.96)
Number of months of physician visits in the previous year 1.08*** (1.07-1.09) 1.07*** (1.06-1.08)
Number of medical institutions in the municipality per 1,000 population 1.36 (0.94-1.97) 1.12 (0.77-1.63)
Need factors
Symptoms, yes 1.26*** (1.18-1.35) 1.17*** (1.10-1.25)
BMI (kg/m2) (ref. < 25)
 25-30 1.04 (0.98-1.10) 0.95 (0.90-1.01)
 ≥30 1.14* (1.004-1.30) 0.96 (0.84-1.10)
Health checkup results
 Hypertension (ref. no hypertension) 1.17*** (1.09-1.25) 1.08* (1.01-1.15)
 Hyperglycemia (ref. no hyperglycemia) 2.08*** (1.85-2.34) 1.89*** (1.66-2.16)
 Liver dysfunction (ref. no liver dysfunction) 1.34*** (1.19-1.50) 1.43*** (1.28-1.59)
 Proteinuria (ref. no proteinuria) 2.10*** (1.77-2.49) 1.73*** (1.44-2.07)
 Glycosuria (ref. no glycosuria) 1.99*** (1.64-2.41) 1.32** (1.07-1.61)
Prior prescriptions within one year before the health checkup
 Antihypertensive (ref. no antihypertensive) 1.86*** (1.68-2.05) 1.22*** (1.09-1.35)
 Antidiabetic (ref. no antidiabetic) 1.71** (1.15-2.54) 0.57* (0.36-0.90)
 Antigout (ref. no antigout) 1.82*** (1.46-2.26) 1.35* (1.07-1.71)
 Antidepressant (ref. no antidepressant) 1.88*** (1.59-2.22) 1.32* (1.10-1.58)
Result of the health checkup in the previous fiscal year (ref. no dyslipidemia)
 Dyslipidemia 0.97 (0.91-1.02) 0.996 (0.94-1.05)
 No health checkup in the previous fiscal year 1.26*** (1.15-1.37) 1.36*** (1.26-1.47)
Number of dyslipidemias at the health checkup 1.17** (1.05-1.30) 1.14* (1.01-1.29)
Health behaviors
 Current smoking, yes 0.84** (0.76-0.93) 0.97 (0.88-1.08)
 Frequency of alcohol consumption (ref. rarely)
  Every day 0.85*** (0.79-0.92) 0.92 (0.85-1.002)
  Occasionally 0.86*** (0.80-0.92) 0.91* (0.85-0.98)
Table 4. Adjusted Odds Ratios for Attendance at a Follow-Up Physician Visit for Dyslipidemia, among Those with High LDL-C.

From: Factors Associated with Non-attendance at a Follow-up Visit for Dyslipidemia Identified at Health Checkups: A Retrospective Cohort Study in a Japanese Prefecture

n = 31,084 Unadjusted OR (95% CI) Adjusted OR (95% CI)
Predisposing factors
Age group (years) (ref. 40-49 years old)
 50-59 1.28*** (1.12-1.47) 1.22** (1.06-1.42)
 60-69 1.62*** (1.45-1.82) 1.49*** (1.33-1.66)
 70-74 1.88*** (1.62-2.17) 1.65*** (1.42-1.91)
Male sex 0.79*** (0.74-0.84) 0.81*** (0.76-0.86)
Enabling factors
Place of health checkups (ref. medical institution)
 Public facility 0.79*** (0.73-0.86) 0.86*** (0.80-0.93)
Number of months of physician visits in the previous year 1.08*** (1.08-1.09) 1.07*** (1.06-1.08)
Number of medical institutions in the municipality per 1,000 population 1.39 (0.96-2.02) 1.12 (0.76-1.64)
Need factors
Symptoms, yes 1.26*** (1.18-1.35) 1.17*** (1.10-1.25)
BMI (kg/m2) (ref. < 25)
 25-30 1.04 (0.97-1.11) 0.95 (0.88-1.01)
 ≥30 1.13 (0.99-1.29) 0.95 (0.84-1.08)
Health checkup results
 Hypertension (ref. no hypertension) 1.19*** (1.11-1.27) 1.07* (1.001-1.15)
 Hyperglycemia (ref. no hyperglycemia) 2.11*** (1.85-2.42) 1.91*** (1.63-2.24)
 Liver dysfunction (ref. no liver dysfunction) 1.33*** (1.16-1.52) 1.38*** (1.21-1.57)
 Proteinuria (ref. no proteinuria) 2.09*** (1.73-2.52) 1.73*** (1.41-2.11)
 Glycosuria (ref. no glycosuria) 2.01*** (1.65-2.45) 1.34** (1.09-1.66)
Prior prescriptions within one year before the health checkup
 Antihypertensive (ref. no antihypertensive) 1.83*** (1.66-2.02) 1.23*** (1.11-1.37)
 Antidiabetic (ref. no antidiabetic) 1.81** (1.22-2.68) 0.61* (0.39-0.95)
 Antigout (ref. no antigout) 1.90*** (1.48-2.45) 1.57** (1.19-2.06)
 Antidepressant (ref. no antidepressant) 1.86*** (1.56-2.23) 1.25* (1.03-1.53)
Results of the health checkup in the previous fiscal year (ref. no dyslipidemia)
 Dyslipidemia 0.98 (0.93-1.04) 0.86*** (0.79-0.92)
 No health checkup in the previous fiscal year 1.27*** (1.16-1.39) 1.18*** (1.08-1.30)
Number of dyslipidemias at the health checkup 1.13* (1.001-1.28) 1.13 (0.99-1.30)
LDL-C level (mg/dL) (ref. 140-160 mg/dL)
 160-180 1.23*** (1.13-1.34) 1.30*** (1.19-1.43)
 ≥180 1.66*** (1.49-1.86) 1.82*** (1.61-2.07)
Health behaviors
 Current smoking, yes 0.83*** (0.75-0.92) 0.98 (0.88-1.09)
 Frequency of alcohol consumption (ref. rarely)
  Every day 0.82*** (0.75-0.89) 0.92 (0.84-1.01)
  Occasionally 0.85*** (0.79-0.91) 0.91** (0.85-0.98)
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