Table 1. List of Commercial Software Packages Providing Automated Measurements or Diagnosis.

From: AI in Echocardiography: State-of-the-art Automated Measurement Techniques and Clinical Applications

Company Software package AI-empowered tools
Siemens Medical Solutions Inc., USA syngo Auto Left Heart, Acuson S2000 US System Auto EF, Auto LV and LA volumes, Auto Strain for manually selected views
GE Healthcare, Inc., USA Ultra Edition Package, Vivid Ultrasound Systems Auto EF, Auto LV and LA volumes, Auto Strain for manually selected views
TOMTEC Imaging Systems GmbH, Germany Tomtec-Arena/Tomtec-Zero Auto EF, Auto LV and LA volumes, Auto Strain for manually selected views
Ultromics Ltd., United Kingdom Echo Go/Echo Go Pro Auto EF, Auto LV and LA volumes, Auto Strain, Auto identification of CHD (fully automated)
Dia Imaging Analysis Ltd., Israel DiaCardio’s LVivoEF Software/LVivo Seamless Auto EF and Auto Standard Echo View Identification (fully automated)
Caption Health, Inc., USA The Caption Guidance Software AI tool for assisting to capture images of a patient’s heart
Butterfly Network, USA Butterfly Garden Auto EF, Auto Standard Echo View Identification, etc.
US2.ai, Singapore US2.ai Auto Standard Echo and Strain (fully automated)
Report generation based on guideline criteria
Table 2. Time Efficiency of Automated vs. Manual Echocardiographic Methods.

From: AI in Echocardiography: State-of-the-art Automated Measurement Techniques and Clinical Applications

Authors Year Target Measurement Vendor Manual/automated measurement time Time saved (%) Notes
Knackstedt et al.(16) 2015 255 patients EF and LS TomTec Manual: Not specified - The fully automated system provided rapid and reproducible EF and LS measurements with 0% variability in automated measurements. Good agreement with manual methods was observed.
Automated: 8 ± 1 s
Lang et al.(10) 2021 200 subjects 16 parameters
LVDd, LVDs, IVS, LVPW, LVOTd, LVOT-VTI, LVEDV (A2C, A4C), LVESV (A2C, A4C), LAV (A2C, A4C), E, A, e’ (sep, lat),
CNN model Average 41% Reduced the variability of most parameters to below 10%.
11′33″/6′48″
Mor-Avi et al.(31) 2023 12 subjects by ten experts 20 parameters
LVDd, LVDs IVS, LVPW, LVOTd, LVOT-VTI, LVEDV (A2C, A4C), LVESV (A2C, A4C), EF, LAV (A2C, A4C), E, A, e’ (sep, lat)
Novel AI software developed collaboratively by TOMTEC Average 43% DL algorithm showed good agreement with reference technique. Manual revisions improved accuracy slightly. Significant reduction in inter-reader variability.
12′00″/6′49″
Olaisen et al.(27) 2024 50 consecutive patients LVEDV, LVESV, and EF Novel AI software (real-time application) Median 77% Test-retest reproducibility was superior in inter-observer scenarios and non-inferior in intra-observer scenarios. AI measurements showed good agreement with reference measurements in both real-time and large research databases.
7′30″/1′54″
Hirata et al.(38) 2024 23 consecutive patients with varying image quality and conditions by expert 30 parameters
LVDd, LVDs IVS, LVPW, LVEDV (A2C, A4C), LVESV (A2C, A4C), LAV (A2C, A4C), EF, SV, LVOTd, E, A, DT, e’ (sep, lat), a’ (sep, lat), s’(sep, lat), TRV, TAPSE, TAM, LVOT VTI, LVOT peakV, RVOT peakV, AoVmax
US2.ai software Average 51% Significant time reduction observed, especially with a good image quality. Manual adjustments required for poor image quality.
5′25″/2′39″
Shiokawa et al.(37) 2024 30 consecutive patients LVDd, LVDs IVS, LVPW, E, A, DT, e’ (sep, lat), a’ (lat), LVOT VTI, LVOT peakV Philips Healthcare Average 27.6% AI significantly reduced measurement time for experts and beginners, less so for intermediates.
1′22″/0′59″
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