| n = 55 | |
|---|---|
| Sex, male, n (%) | 35 (63.6) |
| Age (years) | 68.2 ± 12.3 |
| <75years, n (%) | 35 (63.6) |
| ≥75years, n (%) | 20 (36.4) |
| Weight (kg) | 69.1 ± 14.0 |
| Body mass index (kg/m2) | 25.7 ± 4.5 |
| Morning home SBP (mmHg) | 143.6 ± 7.0 |
| Morning home DBP (mmHg) | 86.9 ± 12.3 |
| Current smoker, n (%) | 3 (5.5) |
| Other complications, n (%) | |
| Type 2 diabetes mellitus | 5 (9.2) |
| Dyslipidemia | 33 (60.0) |
| Hyperuricemia | 18 (32.7) |
| Coronary artery disease | 6 (10.9) |
| Stroke | 3 (5.5) |
| Sleep apnea syndrome | 8 (14.5) |
| Chronic kidney disease | 10 (18.2) |
| Antihypertensive drugs, n (%) | |
| Calcium channel blockers | 55 (100) |
| Angiotensin receptor blockers | 55 (100) |
| Angiotensin-converting enzyme inhibitors | 0 (0) |
| Diuretics | 2 (3.6) |
| β blockers | 5 (9.1) |
| Mineralocorticoid receptor antagonists | 7 (12.7) |
| Others | 0 (0) |
| Baseline | 48 week | P-value | |
|---|---|---|---|
| Pulse rate (bpm) | 74.8 ± 11.0 | 69.5 ± 9.7 | <0.001 |
| eGFRcreat (mL/min/1.73m2) | 66.1 ± 14.5 | 65.4 ± 13.1 | 0.33 |
| Serum potassium concentration (mEq/L) | 4.3 ± 0.3 | 4.3 ± 0.3 | 0.39 |
| Serum uric acid concentration (mg/dL) | 5.9 ± 1.1 | 5.5 ± 1.0 | <0.001 |
| Plasma BNP concentration (pg/mL) | 27.8 ± 21.2 | 28.9 ± 24.5 | 0.39 |
| Hemoglobin A1c value (%) | 5.8 ± 0.5 | 5.8 ± 0.5 | 0.42 |
