Table 1. Summary of Blood Pressure Variability Metrics: Calculation Methods, Units, and Key Characteristics.

From: Unfolding the Tapestry of Blood Pressure Variability: Revealing Hidden Dimensions

Metric name Calculation method Unit Key characteristics
Max-Min Difference Maximum BP value minus minimum BP value over a period mmHg Simple measure of range; sensitive to extreme values
Standard Deviation (SD) Square root of the average squared deviation from the mean mmHg Captures overall dispersion; influenced by mean BP level
Coefficient of Variation (CV) SD divided by mean BP, multiplied by 100 % Standardizes variability relative to mean BP; expressed as a percentage
Variation Independent of Mean (VIM) SD divided by mean BP to the power x, multiplied by population mean to the power x (mmHg) Assesses variability independently of mean BP; adjusts for baseline BP differences
Average Successive Variability / Average Real Variability (ARV) Mean of the absolute differences between successive BP measurements mmHg Reflects short-term or visit-to-visit fluctuations between consecutive readings; ARV term often used in clinical contexts to reduce overestimation from outliers
Standard Deviation about Regression Line (SDreg) SD of the residuals from the regression line of BP over time mmHg Measures variability around long-term BP trends; removes influence of systematic trends
Root Mean Square of Successive Differences (RMSSD) Square root of the mean of the squared successive BP differences mmHg Captures beat-to-beat or short-term variability; emphasizes rapid fluctuations
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