| All group | Non - IDE group | IDE group | p-value | ||
|---|---|---|---|---|---|
| n=76 | n=63 | n=13 | |||
| Age (year) | 75.5 (9.31) | 75.0 (1.2) | 77.5 (2.8) | 0.42 | |
| Sex [men, (n)%] | 48 (63.2) | 41 (65.1) | 7 (53.8) | 0.53 | |
| BMI (kg/m2) | 21.4 (4.2) | 22 (0.8) | 21 (0.9) | 0.42 | |
| GNRI | 81.6 (9.1) | 82.4 (1.2) | 80.3 (2.4) | 0.44 | |
| Prevalence of malnutrition (GNRI < 91.2) [(n)%] | 58 (87.9) | 45 (84.9) | 13 (100) | 0.12 | |
| Rehabilitation time (min/day) | All | 39.1 (1.9) | 37.0 (1.9) | 49.0 (5.6) | 0.01 |
| HD days | 40.9 (2.0) | 38.8 (1.8) | 51.7 (6.8) | 0.01 | |
| Non-HD days | 47.6 (2.5) | 46.4 (2.7) | 53.0 (6.3) | 0.31 | |
| HDS-R (points) | 25.7 (3.2) | 25.8 (0.38) | 25.1 (0.78) | 0.42 | |
| Laboratory Data | |||||
| Alb (g/dL) | 2.9 (0.4) | 3.0 (0.1) | 2.8 (0.2) | 0.41 | |
| BUN (mg/dL) | 41.9 (15.2) | 42.1 (1.6) | 40.8 (6.6) | 0.85 | |
| Cre (mg/dL) | 6.9 (2.1) | 7.2 (0.3) | 5.9 (0.5) | 0.02 | |
| Na (mEq/L) | 134.7 (3.4) | 135.1 (0.4) | 133.1 (0.9) | 0.05 | |
| K (mEq/L) | 3.8 (0.5) | 3.9 (0.1) | 3.5 (0.1) | 0.04 | |
| Cl (mEq/L) | 101.5 (3.8) | 101.9 (0.5) | 99.6 (1.1) | 0.07 | |
| P (mg/dL) | 3.7 (1.2) | 3.8 (0.2) | 3.3 (0.3) | 0.11 | |
| Ca (mg/dL) | 9.1 (0.9) | 9.1 (0.1) | 9.2 (0.2) | 0.71 | |
| eGFR (mL/min/1.73m2) | 6.8 (2.5) | 6.5 (0.3) | 8.1 (0.9) | 0.11 | |
| CRP (mg/dL) | 0.89 (1.24) | 0.96 (0.17) | 0.72 (0.45) | 0.60 | |
| Hb (g/dL) | 10.3 (1.3) | 10.3 (0.2) | 10.3 (0.4) | 0.91 | |
| INT-PTH | 132.3 (116.0) | 136.9 (18.1) | 126.7 (41.7) | 0.83 | |
| Hemodialysis duration (months) | 87.2 (88.8) | 91.2 (13.2) | 55.5 (21.7) | 0.16 | |
| Hemodialysis Time (min) | 229.0 (22.4) | 230 (2.7) | 223.8 (7.3) | 0.43 | |
| Kt/v | 1.35 (0.32) | 1.36 (0.04) | 1.33 (0.09) | 0.77 | |
| %CGR (%) | 68.3 (25.6) | 69.2 (3) | 63.6 (9.3) | 0.57 | |
| nPCR (g/kg/day) | 0.66 (0.15) | 0.65 (0.02) | 0.70 (0.06) | 0.43 | |
| Reason for rehabilitation [Yes, n(%)] | |||||
| Orthopedic | 53 (69.7) | 44 (69.8) | 9 (69.2) | 0.62 | |
| Pulmonary | 10 (13.2) | 6 (9.5) | 0 (0.0) | ||
| Neurologic | 6 (7.9) | 8 (12.7) | 2 (15.4) | ||
| Deconditioning | 7 (9.2) | 5 (7.9) | 2 (15.4) | ||
| Conditions requiring HD treatment [Yes, n(%)] | |||||
| Diabetic nephropathy | 27 (35.5) | 21 (33.3) | 6 (46.2) | 0.24 | |
| Nephrosclerosis | 10 (13.2) | 9 (14.3) | 1 (7.7) | ||
| Chronic glomerulonephritis | 2 (2.6) | 1 (1.6) | 1 (7.7) | ||
| Other | 11 (14.5) | 8 (12.7) | 3 (23.1) | ||
| Unknown | 26 (34.2) | 24 (38.1) | 2 (15.4) | ||
| Comorbidity [Yes, (%)] | |||||
| Diabetes mellitus | 47 (61.8) | 39 (61.9) | 8 (61.5) | 1.00 | |
| Cancer | 8 (10.5) | 7 (11.1) | 1 (7.7) | 1.00 | |
| Ischemic heart disease | 29 (38.2) | 25 (39.7) | 4 (30.8) | 0.76 | |
| Hypertension | 30 (39.5) | 23 (36.5) | 7 (53.8) | 0.35 | |
| Cerebrovascular disease | 21 (27.6) | 19 (30.2) | 2 (15.4) | 0.50 | |
| Arteriosclerosis obliterans | 15 (19.7) | 14 (22.2) | 1 (7.7) | 0.44 | |
| Valvular Heart Disease | 4 (5.3) | 3 (4.8) | 1 (7.7) | 0.54 | |
| Admission Physical function | Reference Value | ||||
| Grip strength (kg) | Men: 28, Women 18 |
15.4 (5.3) | 15.4 (0.8) | 14.8 (1.5) | 0.71 |
| IKES (%) | 40 | 26.4 (9.5) | 25.76 (1.2) | 28.76 (2.7) | 0.38 |
| 10MWS (m/s) | 1.0 | 0.66 (0.27) | 0.65 (0.05) | 0.72 (0.1) | 0.52 |
| SPPB (points) | 9 | 2.8 (3.5) | 2.7 (0.3) | 3.3 (0.9) | 0.55 |
| TUG (sec) | 13.5 | 28.5 (21.0) | 28.5 (1.5) | 27.7 (5.3) | 0.88 |
| Barthel Index (points) | 75 | 53.9 (21.0) | 55.7 (2.9) | 50.8 (5.4) | 0.43 |
| All | Non-IDE group | IDE group | |||
|---|---|---|---|---|---|
| n=76 | n=63 | n=13 | p-value | ||
| Length of hospital stays (days) | All | 49.9 (1.8) | 48.6 (1.9) | 56.2 (4.0) | 0.097 |
| HD days | 21.3 (0.8) | 20.7 (0.8) | 23.9 (1.8) | 0.105 | |
| Non-HD days | 21.6 (0.8) | 21.1 (0.8) | 24.2 (1.7) | 0.111 | |
| Barthel Index Gain (points) | 20.2 (1.6) | 18.1 (1.4) | 30.4 (5.4) | < 0.001 | |
| Barthel Index efficiency (points/days) | 0.41 (0.05) | 0.38 (0.05) | 0.54 (0.08) | 0.114 | |
| Discharge | |||||
| Grip strength (kg) | 15.9 (6.3) | 16.8 (1.9) | 14.2 (2.7) | 0.404 | |
| IKES (%) | 28.7 (12.5) | 28.1 (1) | 32 (4.3) | 0.368 | |
| 10MWS (m/s) | 0.70 (0.26) | 0.69 (0.05) | 0.77 (0.1) | 0.516 | |
| SPPB (points) | 4.9 (3.9) | 4.8 (0.4) | 5.2 (1.0) | 0.695 | |
| TUG (sec) | 20.4 (8.6) | 20.3 (0.7) | 20.9 (2.8) | 0.819 | |
| Barthel Index (points) | 69.2 (23.5) | 65.6 (4.7) | 81.2 (3.7) | 0.010 | |
| Non -IDE group (control) | IDE group | ΔIDE - ΔNon - IDE group | ||||
|---|---|---|---|---|---|---|
| ΔPost - Pre (95CI) | p-value | ΔPost - Pre (95CI) | p-value | Difference (95CI) | p-value | |
| Grip strength (kg) | 0.85 (-0.27 to 1.97) | 0.169 | 1.55 (1.46 to 1.65)* | 0.017 | 2.10 (-0.40 to 4.60) | 0.115 |
| IKES (%) | -1.95 (-5.46 to 1.55) | 0.299 | 0.07 (-0.14 to 0.29) | 0.987 | 7.40 (-2.20 to 17.02) | 0.149 |
| 10MWS (m/s) | 0.04 (-0.03 to 0.13) | 0.279 | 0.30 (0.12 to 0.47) | 0.073 | 0.25 (0.05 to 0.45)* | 0.036 |
| SPPB (points) | 1.06 (-0.003 to 2.116) | 0.096 | 2.44 (1.34 to 3.55)* | 0.006 | 1.23 (-0.48 to 2.94) | 0.192 |
| TUG (sec) | -10.80 (-19.49 to -2.12)* | 0.035 | -4.08 (-5.26 to -2.90) | 0.975 | -3.07 (-20.74 to 14.60) | 0.739 |
| Barthel Index (points) | 16.26 (9.59 to 22.93)* | 0.000 | 28.90 (19.76 to 37.94)* | 0.000 | 13.67 (0.96 to 26.38)* | 0.047 |
