Table 1. Clinical Characteristics of Pregnancies with Macrosomia Compared with Deliveries with Neonatal Birth Weight of 3,500-3,999 g.

From: Clinical Significance of Pregnancies with Macrosomia (Birth Weight ≥ 4,000 g) Compared with Deliveries with Neonatal Birth Weight of 3,500-3,999 g

Control Macrosomia P-value
Total number 1139 136
Maternal age < 20 years 10 (0.9) 2 (1.5) 0.50
Maternal age ≥ 35 years 303 (26.6) 48 (35.3) 0.03
Nulliparity 498 (43.7) 50 (36.5) 0.12
Maternal height ≥ 1.6 m 490 (43.0) 63 (46.3) 0.46
Maternal body mass index at prepregnancy ≥ 25 387 (34.0) 55 (40.4) 0.13
Gestational weight gain ≥ 15 kg 68 (6.0) 6 (4.4) 0.46
Gestational age at delivery ≥ 41 weeks 342 (30.0) 58 (42.6) <0.01
Glucose intolerance 26 (2.3) 6 (4.4) 0.13
Neonatal sex: male 712 (62.5) 87 (64.0) 0.74
Table 2. Perinatal Outcomes of Pregnancies with Macrosomia Compared with Deliveries with Neonatal Birth Weight of 3,500-3,999 g.

From: Clinical Significance of Pregnancies with Macrosomia (Birth Weight ≥ 4,000 g) Compared with Deliveries with Neonatal Birth Weight of 3,500-3,999 g

Control Macrosomia P-value OR 95% CI
Total number 1139 136
Elective cesarean delivery
 Yes 88 (7.7) 21 (15.4) < 0.01 2.18 1.3-3.6
 No 1051 (92.3) 115 (84.6) Reference 1
Emergent cesarean delivery
 Yes 90 (7.9) 16 (11.8) 0.12 1.55 0.9-2.3
 No 1049 (92.1) 120 (88.2) Reference 1
Vaginal delivery
 Yes 961 (84.4) 99 (72.8) < 0.01 0.50 0.3-0.8
 No 178 (15.6) 37 (27.2) Reference 1
 Normal delivery 844 (/961, 87.8) 85 (/99, 85.9) Reference 1
 Vacuum extraction/forceps delivery 100 (/961, 10.4) 8 (/99, 8.1) 0.47 0.76 0.4-1.6
 Shoulder dystocia 3 (/961, 0.3) 4 (/99, 4.0) < 0.01 13.24 3.3-52.4
 Severe perineal lacerations 14 (/961, 1.5) 2 (/99, 2.0) 0.65 1.42 0.4-5.6
Postpartum hemorrhage requiring transfusion
6 (0.5) 2 (1.5) 0.19 2.82 0.7-12.4
1133 (99.5) 134 (98.5) Reference 1
Perinatal death
 Yes 1 (0.1) 0 (0) 0.73 0 0-32.3
 No 1138 (99.9) 136 (100) Reference 1
Neonatal asphyxia
 Yes 15 (1.3) 10 (7.4) < 0.01 5.95 2.7-13.3
 No 1124 (98.7) 126 (92.6) Reference 1
Umbilical artery pH
 ≥7.0 1133 (99.5) 134 (98.5) Reference 1
 <7.0 6 (0.5) 2 (1.5) 0.19 2.82 0.7-12.4
Neonatal hypoglycemia
 Yes 98 (8.6) 19 (14.0) 0.06 1.73 1.0-2.9
 No 1041 (91.4) 117 (86.0) Reference 1
Table 3. Results of the Multivariate Analysis of the Perinatal Outcomes of Pregnancies with Macrosomia.

From: Clinical Significance of Pregnancies with Macrosomia (Birth Weight ≥ 4,000 g) Compared with Deliveries with Neonatal Birth Weight of 3,500-3,999 g

P-value Adjusted OR 95% CI
Elective cesarean delivery 0.13 1.56 0.9-2.8
Vaginal delivery 0.28 0.80 0.6-1.2
Shoulder dystocia in vaginal delivery 0.01 7.11 1.8-29.1
Neonatal asphyxia 0.03 3.03 1.1-8.2
Table 4. Summary of 7 Cases of Shoulder Dystocia.

From: Clinical Significance of Pregnancies with Macrosomia (Birth Weight ≥ 4,000 g) Compared with Deliveries with Neonatal Birth Weight of 3,500-3,999 g

Case Maternal age (y) Parity Gestational age at delivery (w + d) Delivery mode Neonatal sex Birth weight (g) Apgar score at 1 min Umbilical artery pH
1 32 1 40 + 4 Normal delivery Male 3,878 6 7.251
2 33 0 42 + 0 Forceps delivery Male 3,898 7 7.240
3 29 2 39 + 2 Normal delivery Female 3,902 1 7.271
4 36 1 39 + 5 Normal delivery Male 4,024 9 7.238
5 35 2 41 + 6 Normal delivery Male 4,118 4 7.278
6 33 2 41 + 3 Normal delivery Male 4,290 2 7.239
7 32 0 36 + 6 Normal delivery Male 4,436 1 6.949
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