From: Coronary Lesions and Systemic Inflammatory Response Syndrome in Kawasaki Disease
| non-SIRS | SIRS | p-value | |
|---|---|---|---|
| N = 102 | N = 175 | ||
| Gender (male) | 62 (60.8) | 102 (58.3) | 0.71 |
| Age (months) | 25.5 (15.7) | 34.6 (23.9) | < 0.001 |
| Days of illness | 4.12 (1.86) | 4.20 (2.18) | 0.77 |
| Vital signs | |||
| Body temperature (℃) | 38.3 (0.51; 102) | 39.1 (0.70; 175) | < 0.001 |
| Heart rate (bpm) | 152 (22.1; 101) | 159 (25.0; 175) | 0.02 |
| Respiratory rate (/min) | 33.4 (7.83; 87) | 34.6 (9.62; 157) | 0.29 |
| Laboratory findings | |||
| WBC (103/µL) | 12.2 (3.52; 101) | 14.9 (4.82; 174) | < 0.001 |
| Neutrophils (%) | 62.6 (15.5; 101) | 71.1 (15.4; 174) | < 0.001 |
| Platelets (104/µL) | 34.9 (12.7; 100) | 34.3 (12.4; 172) | 0.77 |
| Sodium (mmol/L) | 135 (2.89; 101) | 133 (2.94; 172) | 0.001 |
| AST (U/L) | 64.6 (83.2; 101) | 113 (242; 172) | 0.02 |
| ALT (U/L) | 70.7 (113; 101) | 108 (165; 174) | 0.03 |
| CRP (mg/dL) | 6.29 (4.45; 101) | 7.50 (4.03; 174) | 0.02 |
| Albumin (g/dL) | 3.66 (0.47; 99) | 3.57 (0.40; 170) | 0.09 |
| Total cholesterol (mg/dL) | 148 (24.0; 94) | 144 (27.2; 157) | 0.29 |
| Kobayashi score | 2.93 (2.53; 102) | 3.81 (2.63; 175) | 0.01 |
| Kobayashi score ≥ 5 | 21 (20.6) | 63 (36.0) | 0.007 |
From: Coronary Lesions and Systemic Inflammatory Response Syndrome in Kawasaki Disease
| non-SIRS | SIRS | ||
|---|---|---|---|
| N = 102 | N = 175 | p-value | |
| Z-score of the coronary artery at 1 week of the clinical course | |||
| RCA | 1.36 (1.79) | 1.54 (1.74) | 0.41 |
| LMCA | 1.96 (0.83) | 2.0 (1.07) | 0.74 |
| LAD | 1.25 (1.13) | 1.42 (1.45) | 0.31 |
| Z-score of the coronary artery at 1 month after treatment | |||
| RCA | 0.92 (1.84) | 1.09 (1.73) | 0.45 |
| LMCA | 1.63 (0.92) | 1.54 (1.0) | 0.45 |
| LAD | 0.92 (1.16) | 0.98 (1.48) | 0.71 |
| CAL at week 1 | 8 (7.8) | 31 (17.7) | 0.03 |
| CAL at month 1 | 4 (3.9) | 19 (10.9) | 0.03 |
| IVIG resistancea | 10 (10.5) | 12 (7.0) | 0.36 |
From: Coronary Lesions and Systemic Inflammatory Response Syndrome in Kawasaki Disease
| CAL at week 1 | CAL at month 1 | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p-value | OR | 95% CI | p-value | |
| SIRS | 2.7 | 1.03–7.23 | 0.04 | 3.0 | 0.81–11.1 | 0.10 |
| Kobayashi score variables | ||||||
| Illness days | 1.2 | 0.96–1.39 | 0.13 | 1.2 | 0.98–1.47 | 0.08 |
| CRP | 1.1 | 1.03–1.24 | 0.01 | 1.1 | 0.97–1.22 | 0.14 |
| Neutrophils | 1.0 | 0.98–1.07 | 0.29 | 1.0 | 0.97–1.09 | 0.31 |
| Platelets | 1.0 | 0.97–1.04 | 0.83 | 1.0 | 0.95–1.05 | 0.98 |
| AST | 1.0 | 0.99–1.00 | 0.99 | 1.0 | 0.99–1.00 | 0.65 |
| Sodium | 1.0 | 0.86–1.16 | 0.99 | 0.94 | 0.79–1.13 | 0.52 |
| Months of age | 1.0 | 0.98–1.002 | 0.96 | 1.0 | 0.97–1.02 | 0.81 |
From: Coronary Lesions and Systemic Inflammatory Response Syndrome in Kawasaki Disease
| non-SIRS | SIRS | p-value | |
|---|---|---|---|
| N = 90 | N = 114 | ||
| Gender (male) | 57 (63.3) | 67 (58.8) | 0.51 |
| Age (months) | 24.6 (18.0) | 31.8 (23.4) | 0.01 |
| Z-score of the coronary artery at 1 week of the clinical course | |||
| RCA | 1.18 (1.19) | 1.32 (1.29) | 0.44 |
| LMCA | 1.98 (0.64) | 1.89 (1.01) | 0.51 |
| LAD | 1.17 (0.94) | 1.24 (1.0) | 0.57 |
| Z-score of the coronary artery at 1 month after treatment | |||
| RCA | 0.80 (1.20) | 0.86 (1.21) | 0.71 |
| LMCA | 1.64 (0.71) | 1.44 (0.93) | 0.10 |
| LAD | 0.91 (0.89) | 0.82 (1.03) | 0.52 |
| CAL at week 1 | 5 (5.6) | 18 (15.8) | 0.03 |
| CAL at month 1 | 2 (2.2) | 9 (7.9) | 0.12 |
| IVIG resistance | 14 (15.6) | 16 (14.0) | 0.84 |
