Clinical parameters | Mean ± SD, percentage, or number |
---|---|
Number | 2201 |
Age (years) | 74.1 ± 11.1 |
Male gender (%) | 59.5 |
SBP (mmHg) | 134.9 ± 17.1 |
DBP (mmHg) | 74.1 ± 12.9 |
BMI (kg/m2) | 25.7 ± 4.3 |
eGFR (mL/min/1.73 m2) | 66.3 ± 22.0 |
Obesity (%) | 56.2 |
Hypertension (%) | 85.2 |
Diabetes mellitus (%) | 47.8 |
Dyslipidemia (%) | 71.5 |
Cerebrovascular disease (%) | 46.0 |
Ischemic heart disease (%) | 38.0 |
Heart failure (%) | 19.4 |
Atrial fibrillation (%) | 17.3 |
Chronic kidney disease (%) | 43.8 |
Antihypertensive therapy (%) | 79.7 |
ACE inhibitor (%) | 14.4 |
ARB (%) | 41.9 |
CCB (%) | 52.2 |
Beta-blocker (%) | 21.7 |
Diuretics (%) | 16.5 |
Antithrombotic therapy (%) | 100 |
Acetylsalicylic acid (%) | 68.1 |
P2Y12 receptor inhibitor (%) | 18.0 |
PDE-III inhibitor (%) | 5.7 |
Warfarin (%) | 13.3 |
Direct factor Xa inhibitor (%) | 6.5 |
Direct thrombin inhibitor (%) | 2.8 |
Variable | Achievement of the target blood pressure value | ||
---|---|---|---|
Yes, n (%) | No, n (%) | P-value | |
Age | 0.031 | ||
<75 years | 279 (28.2) | 709 (71.8) | |
≥75 years | 394 (32.5) | 819 (67.5) | |
Gender | 0.008 | ||
Male | 372 (28.4) | 937 (71.6) | |
Female | 301 (33.7) | 591 (66.3) | |
Obesity | <0.001 | ||
Yes | 317 (25.6) | 920 (74.4) | |
No | 356 (36.9) | 608 (63.1) | |
Diabetes mellitus | 0.783 | ||
Yes | 319 (30.3) | 734 (69.7) | |
No | 354 (30.8) | 794 (69.2) | |
Dyslipidemia | 0.049 | ||
Yes | 462 (29.4) | 1112 (70.7) | |
No | 211 (33.7) | 416 (66.4) | |
Cerebrovascular disease | 0.693 | ||
Yes | 314 (31.0) | 699 (69.0) | |
No | 359 (30.2) | 829 (69.8) | |
Ischemic heart disease | 0.021 | ||
Yes | 280 (33.5) | 556 (66.5) | |
No | 393 (28.8) | 972 (71.2) | |
Heart failure | <0.001 | ||
Yes | 184 (43.2) | 242 (56.8) | |
No | 489 (27.6) | 1286 (72.5) | |
Atrial fibrillation | 0.163 | ||
Yes | 128 (33.6) | 253 (66.4) | |
No | 545 (30.0) | 1275 (70.1) | |
Chronic kidney disease | |||
Yes | 300 (31.2) | 663 (68.9) | 0.605 |
No | 373 (30.1) | 865 (69.9) |
Univariate model | Multivariate model | |||||
---|---|---|---|---|---|---|
Variable | Odds ratio | 95% CI | P-value | Odds ratio | 95% CI | P-value |
Age, ≥75 years | 0.818 | 0.681-0.982 | 0.031 | 0.953 | 0.774-1.174 | 0.651 |
Male gender | 1.283 | 1.068-1.541 | 0.008 | 1.263 | 1.035-1.542 | 0.022 |
Obesity | 1.699 | 1.416-2.041 | <0.001 | 1.703 | 1.399-2.075 | <0.001 |
Diabetes mellitus | 1.026 | 0.856-1.230 | 0.783 | 0.917 | 0.751-1.121 | 0.398 |
Dyslipidemia | 1.221 | 1.000-1.487 | 0.049 | 1.241 | 0.987-1.558 | 0.064 |
Cerebrovascular disease | 0.964 | 0.803-1.156 | 0.693 | 0.748 | 0.600-0.932 | 0.010 |
Ischemic heart disease | 0.803 | 0.667-0.967 | 0.021 | 0.737 | 0.587-0.927 | 0.009 |
Heart failure | 0.500 | 0.402-0.622 | <0.001 | 0.493 | 0.385-0.631 | <0.001 |
Atrial fibrillation | 0.845 | 0.669-1.071 | 0.163 | 0.916 | 0.696-1.208 | 0.531 |
eGFR (mL/min/1.73 m2) | 1.004 | 1.000-1.008 | 0.081 | 1.002 | 0.997-1.007 | 0.400 |
Univariate model | Multivariate model | |||||
---|---|---|---|---|---|---|
Variable | Odds ratio | 95% CI | P-value | Odds ratio | 95% CI | P-value |
Age, ≥75 years | 0.795 | 0.515-1.221 | 0.296 | 0.947 | 0.568-1.578 | 0.835 |
Male gender | 1.593 | 1.035-2.455 | 0.034 | 1.462 | 0.914-2.341 | 0.113 |
Obesity | 1.959 | 1.268-3.027 | 0.002 | 2.050 | 1.278-3.301 | 0.003 |
Diabetes mellitus | 1.221 | 0.792-1.896 | 0.367 | 0.909 | 0.557-1.485 | 0.703 |
Dyslipidemia | 1.359 | 0.888-2.087 | 0.158 | 1.433 | 0.862-2.397 | 0.165 |
Cerebrovascular disease | 0.727 | 0.442-1.207 | 0.215 | 0.643 | 0.373-1.112 | 0.114 |
Ischemic heart disease | 0.884 | 0.550-1.433 | 0.612 | 0.873 | 0.502-1.531 | 0.634 |
Heart failure | 0.446 | 0.288-0.688 | <0.001 | 0.419 | 0.257-0.676 | <0.001 |
eGFR (mL/min/1.73 m2) | 1.002 | 0.991-1.013 | 0.752 | 0.997 | 0.985-1.009 | 0.613 |
Univariate model | Multivariate model | |||||
---|---|---|---|---|---|---|
Variable | Odds ratio | 95% CI | P-value | Odds ratio | 95% CI | P-value |
Age, ≥75 years | 0.824 | 0.672-1.008 | 0.060 | 0.945 | 0.751-1.189 | 0.631 |
Male gender | 1.224 | 0.998-1.499 | 0.052 | 1.225 | 0.981-1.528 | 0.073 |
Obesity | 1.668 | 1.363-2.042 | <0.001 | 1.638 | 1.319-2.036 | <0.001 |
Diabetes mellitus | 0.978 | 0.800-1.196 | 0.830 | 0.919 | 0.737-1.145 | 0.451 |
Dyslipidemia | 1.148 | 0.909-1.446 | 0.245 | 1.174 | 0.905-1.520 | 0.224 |
Cerebrovascular disease | 0.971 | 0.794-1.187 | 0.774 | 0.755 | 0.589-0.966 | 0.025 |
Ischemic heart disease | 0.773 | 0.631-0.947 | 0.013 | 0.717 | 0.554-0.927 | 0.011 |
Heart failure | 0.519 | 0.399-0.677 | <0.001 | 0.517 | 0.387-0.691 | <0.001 |
eGFR (mL/min/1.73 m2) | 1.004 | 0.999-1.009 | 0.099 | 1.003 | 0.998-1.008 | 0.281 |