| Factors | Before propensity score matching | After propensity score matching | ||||
|---|---|---|---|---|---|---|
| Nonsarcopenia (n = 260) | Sarcopenia (n = 93) | P-value | Nonsarcopenia (n = 72) | Sarcopenia (n = 72) | P-value | |
| Age (years) | 70 (65-76) | 74 (68-78) | 0.0011 | 74 (68-79) | 74 (68-77) | 0.5485 |
| Sex, male/female | 191/69 | 56/37 | 0.0168 | 45/27 | 45/27 | 1.0000 |
| BMI (kg/m2) | 23.9 (22.3-26.2) | 20.8 (19.3-23.0) | <0.0001 | 22.1 (20.3-23.6) | 21.8 (19.7-23.5) | 0.4745 |
| Diabetes mellitus (%) | 100 (38.4%) | 36 (38.7%) | 0.9663 | 29 (40.2%) | 27 (37.5%) | 0.7324 |
| Hypertension (%) | 152 (58.4%) | 60 (64.5%) | 0.3063 | 43 (59.7%) | 47 (65.2%) | 0.4911 |
| HBs-Ag positive (%) | 54 (20.7%) | 8 (8.6%) | 0.0081 | 5 (6.9%) | 8 (11.1%) | 0.3830 |
| HCV-Ab positive (%) | 105 (40.3%) | 45 (48.3%) | 0.1803 | 35 (48.6%) | 35 (48.6%) | 1.0000 |
| Total cholesterol (mg/dl) | 175 (151-193) | 168 (141-193) | 0.2389 | 175 (151-192) | 171 (143-193) | 0.4047 |
| Albumin (g/dl) | 4.1 (3.8-4.4) | 4.0 (3.7-4.2) | 0.0070 | 4.0 (3.6-4.2) | 4.1 (3.8-4.2) | 0.7362 |
| Total bilirubin (mg/dl) | 0.9 (0.7-1.1) | 0.8 (0.6-1.0) | 0.0326 | 0.8 (0.6-1.1) | 0.8 (0.6-1.0) | 0.6368 |
| Prothrombin time (%) | 93 (85-102) | 93 (86-103) | 0.9674 | 95 (87-105) | 94 (86-105) | 0.7220 |
| Platelet (×104/μl) | 15.6 (11.9-19.2) | 16.8 (13.5-22.7) | 0.0272 | 16.6 (12.5-20.9) | 16.7 (13.1-20.5) | 0.7675 |
| ICGR15 (%) | 11.4 (7.8-18.4) | 9.5 (5.5-16.1) | 0.0300 | 10.1 (6.6-18.4) | 8.5 (4.7-14.9) | 0.0817 |
| Child-Pugh classification, grade B | 11 (4.2%) | 7 (7.5%) | 0.2149 | 2 (2.7%) | 5 (6.9%) | 0.4414 |
| ALBI, grade 2 | 102 (39.2%) | 43 (46.2%) | 0.2386 | 32 (44.4%) | 32 (44.4%) | 1.0000 |
| Total lymphocyte count (/mm3) | 1465 (1131-1898) | 1291 (923-1698) | 0.0229 | 1471 (1082-1789) | 1379 (950-1780) | 0.7162 |
| C-reactive protein (mg/dl) | 0.10 (0.04-0.18) | 0.09 (0.04-0.22) | 0.8250 | 0.10 (0.04-0.25) | 0.09 (0.04-0.20) | 0.4764 |
| AFP (ng/ml) | 5.2 (3.3-18.7) | 14.2 (3.9-388) | 0.0001 | 5.9 (3.1-61.3) | 12.8 (3.9-174) | 0.2369 |
| DCP (mAU/ml) | 37 (22-156) | 80 (28.5-1648) | 0.0006 | 96 (26-1548) | 77 (29-1145) | 0.7745 |
| Tumor size (cm) | 2.5 (1.6-4.0) | 3.2 (1.8-6.7) | 0.0042 | 3.5 (2.2-6.0) | 2.8 (1.7-5.5) | 0.2327 |
| Solitary/multiple | 202/58 | 63/30 | 0.0570 | 54/18 | 50/22 | 0.4568 |
| Macrovascular invasion (%) | 13 (5.0%) | 6 (6.4%) | 0.6001 | 4 (5.5%) | 3 (4.1%) | 0.6964 |
| BCLC staging, B or C (%) | 35 (13.4%) | 24 (25.8%) | 0.0062 | 15 (20.8%) | 15 (20.8%) | 1.0000 |
| Gross classification, single nodular type (%) | 189 (73.5%) | 63 (68.4%) | 0.3523 | 48 (66.6%) | 51 (70.8%) | 0.5896 |
| Factors | Before propensity score matching | After propensity score matching | ||||
|---|---|---|---|---|---|---|
| Nonsarcopenia (n = 260) | Sarcopenia (n = 93) | P-value | Nonsarcopenia (n = 72) | Sarcopenia (n = 72) | P-value | |
| Anatomical liver resection (%) | 109 (41.9%) | 48 (51.6%) | 0.1066 | 32 (44.4%) | 32 (44.4%) | 1.0000 |
| Major liver resection (%) | 29 (11.1%) | 16 (17.2%) | 0.1332 | 16 (22.2%) | 8 (11.1%) | 0.0736 |
| Laparoscopic liver resection (%) | 102 (39.2%) | 29 (31.1%) | 0.1680 | 21 (29.1%) | 20 (27.7%) | 0.8535 |
| Duration of surgery (min) | 228 (168-284) | 247 (166-323) | 0.2534 | 240 (176-277) | 238 (149-297) | 0.7951 |
| Blood loss (g) | 220 (100-500) | 250 (126-800) | 0.0859 | 291 (100-536) | 231 (82-652) | 0.9649 |
| Postoperative complications (%) | 35 (13.4%) | 16 (17.2%) | 0.3783 | 8 (11.1%) | 14 (19.4%) | 0.1646 |
| Postoperative hospital stay (days) | 10 (8-13) | 11 (9-15) | 0.0096 | 11 (8-14) | 11 (8-15) | 0.4162 |
| Poor differentiation (%) | 66 (25.8%) | 34 (36.5%) | 0.0515 | 23 (32.3%) | 26 (36.1%) | 0.6396 |
| Microscopic vascular invasion (%) | 44 (17.1%) | 20 (21.5%) | 0.3486 | 17 (23.6%) | 12 (16.6%) | 0.2988 |
| Microscopic intrahepatic metastasis (%) | 39 (15.2%) | 24 (25.8%) | 0.0242 | 11 (15.2%) | 17 (23.6%) | 0.2065 |
| F3 or F4 (%) | 99 (38.0%) | 33 (36.2%) | 0.7586 | 19 (26.3%) | 27 (38.5%) | 0.1209 |
