Table 1. Patient Characteristics of Asymptomatic Patients at the Time of ERCP (Groups A and B) and Symptomatic Patients (Group C).

From: Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis after Conservative Treatment for Symptomatic Bile Duct Stones

All patients Propensity score-matched groups
Groups A and B Group C P-value Groups A and B Group C P-value
(n = 118) (n = 1225) (n = 114) (n = 114)
Age [mean (SD)] 74.8 (9.8) 75.0 (14.4) 0.85 75.0 (9.7) 74.4 (15.0) 0.70
Female (%) 55 (46.6) 581 (47.4) 0.92 54 (47.4) 48 (42.1) 0.51
Dialysis (%) 4 (3.4) 36 (2.9) 0.77 4 (3.5) 3 (2.6) 1.0
Billroth-1 reconstruction (%) 6 (5.1) 30 (2.4) 0.12 6 (5.3) 6 (5.3) 1.0
Non-expert endoscopists (%) 24 (20.3) 184 (15.0) 0.14 22 (19.3) 15 (13.2) 0.28
Successful biliary cannulation (%) 115 (97.5) 1212 (98.9) 0.16 111 (97.4) 112 (98.2) 1.0
Periampullary diverticulum (%) 38 (32.2) 367 (30.0) 0.60 37 (32.5) 30 (26.3) 0.38
Normal serum bilirubin (%) 112 (94.9) 461 (37.6) <0.001 108 (94.7) 109 (95.6) 1.0
Non-dilated CBD (<10 mm) (%) 41 (34.7) 494 (40.3) 0.28 40 (35.1) 39 (34.2) 1.0
Contrast-assisted cannulation (%) 87 (73.7) 876 (71.5) 0.67 84 (73.7) 82 (71.9) 0.88
Wire-guided cannulation (%) 8 (6.8) 126 (10.3) 0.26 8 (7.0) 7 (6.1) 1.0
PGW-assisted cannulation (%) 11 (9.3) 166 (13.6) 0.25 10 (8.8) 11 (9.6) 1.0
Difficult biliary cannulation >10min (%) 43 (36.4) 289 (23.6) 0.003 40 (35.1) 39 (34.2) 1.0
Pancreatic injection (%) 60 (50.8) 533 (43.5) 0.15 57 (50.0) 58 (50.9) 1.0
Precut sphincterotomy (%) 12 (10.2) 56 (4.6) 0.014 12 (10.5) 14 (12.3) 0.84
Use of balloon catheter (%) 94 (79.7) 979 (79.9) 0.91 92 (80.7) 90 (78.9) 0.87
Use of basket catheter (%) 65 (55.1) 553 (45.1) 0.042 62 (54.4) 61 (53.5) 1.0
Mechanical lithotripsy (%) 17 (14.4) 197 (16.1) 0.70 16 (14.0) 16 (14.0) 1.0
Biliary stent placement (%) 83 (70.3) 1072 (87.5) <0.001 82 (71.9) 85 (74.6) 0.77
EST (%) 86 (72.9) 893 (72.9) 1.0 82 (71.9) 80 (70.2) 0.88
EPBD (%) 7 (5.9) 132 (10.8) 0.11 7 (6.1) 8 (7.0) 1.0
EPLBD (%) 22 (18.6) 187 (15.3) 0.35 22 (19.3) 24 (21.1) 0.87
Prophylactic pancreatic stent placement (%) 16 (13.6) 166 (13.6) 1.0 16 (14.0) 15 (13.2) 1.0
Rectal NSAIDs (%) 10 (8.5) 108 (8.8) 1.0 9 (7.9) 8 (7.0) 1.0
Post-cholecystectomy (%) 27 (22.9) 129 (10.5) <0.001 25 (21.9) 30 (26.3) 0.54
Presence of gallstones (%) 60 (50.8) 759 (62.0) 0.023 58 (50.9) 56 (49.1) 0.90
Large stones (>10 mm) (%) 14 (11.9) 234 (19.1) 0.062 14 (12.3) 15 (13.2) 1.0
Number of CBDS [mean (SD)] 2.7 (3.9) 2.2 (2.5) 0.15 2.8 (4.0) 2.5 (3.0) 0.54
Procedure time, min [mean (SD)] 31.5 (18.8) 26.1 (14.9) 0.003 31.5 (19.0) 31.2 (10.8) 0.91
Table 2. PEP Incidence Rates in Asymptomatic Patients at the Time of ERCP (Groups A and B) and Symptomatic Patients (Group C).

From: Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis after Conservative Treatment for Symptomatic Bile Duct Stones

All patients Propensity score-matched groups
Groups A and B Group C P-value Groups A and B Group C P-value
(n = 118) (n = 1225) (n = 114) (n = 114)
PEP (%) 15 (12.7) 35 (2.9) <0.001 15 (13.2) 5 (4.4) 0.033
Table 3. Patient Characteristics in Groups A and B.

From: Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis after Conservative Treatment for Symptomatic Bile Duct Stones

Group A Group B P-value
(n = 77) (n = 41)
Age [mean (SD)] 74.3 (9.1) 75.8 (11.0) 0.47
Female (%) 33 (42.9) 22 (53.7) 0.33
Dialysis (%) 3 (3.9) 1 (2.4) 1.0
Billroth-1 reconstruction (%) 3 (3.9) 3 (7.3) 0.42
Non-expert endoscopists (%) 17 (22.1) 7 (17.1) 0.63
Successful biliary cannulation (%) 74 (96.1) 41 (100.0) 0.55
Periampullary diverticulum (%) 25 (32.5) 13 (31.7) 1.0
Normal serum bilirubin (%) 74 (96.1) 38 (92.7) 0.42
Non-dilated CBD (<10 mm) (%) 28 (36.4) 13 (31.7) 0.69
Contrast-assisted cannulation (%) 56 (72.7) 31 (75.6) 0.83
Wire-guided cannulation (%) 7 (9.1) 1 (2.4) 0.26
PGW-assisted cannulation (%) 7 (9.1) 4 (9.8) 1.0
Difficult biliary cannulation >10min (%) 29 (37.7) 14 (34.1) 0.84
Pancreatic injection (%) 42 (54.5) 18 (43.9) 0.34
Precut sphincterotomy (%) 7 (9.1) 5 (12.2) 0.75
Use of balloon catheter (%) 60 (77.9) 34 (82.9) 0.63
Use of basket catheter (%) 43 (55.8) 22 (53.7) 0.85
Mechanical lithotripsy (%) 9 (11.7) 8 (19.5) 0.28
Biliary stent placement (%) 56 (72.7) 27 (65.9) 0.53
EST (%) 59 (76.6) 27 (65.9) 0.28
EPBD (%) 2 (2.6) 5 (12.2) 0.049
EPLBD (%) 13 (16.9) 9 (22.0) 0.62
Prophylactic pancreatic stent placement (%) 12 (15.6) 4 (9.8) 0.57
Rectal NSAIDs (%) 7 (9.1) 3 (7.3) 1.0
Post-cholecystectomy (%) 16 (20.8) 11 (26.8) 0.50
Presence of gallstones (%) 41 (53.2) 19 (46.3) 0.56
Large stones (> 10 mm) (%) 10 (13.0) 4 (9.8) 0.77
Number of CBDS [mean (SD)] 2.4 (3.0) 3.3 (5.2) 0.33
Procedure time, min [mean (SD)] 32.3 (18.8) 30.0 (19.0) 0.53
Table 4. Comparing the Incidence and Severity of Post-ERCP Pancreatitis between Groups A and B.

From: Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis after Conservative Treatment for Symptomatic Bile Duct Stones

Group A Group B P-value
(n = 77) (n = 41)
Post-ERCP pancreatitis (%) 9 (11.7%) 6 (14.6%) 0.77
Severity 1.0
 Mild (%) 5 (55.6%) 3 (50.0%)
 Moderate (%) 3 (33.3%) 3 (50.0%)
 Severe (%) 1 (11.1%) 0 (0%)
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