Table 1. Demographic and Clinical Characteristics of 18 SMID Patients.

From: Evaluation of eGFRs to Calculate Kidney Function in Adults with Severe Motor and Intellectual Disabilities

Number of cases
Sex Male 10
Female 8
Age 20~39 years 9
40~59 years 7
60~79 years 2
Underlying disease Cerebral palsy 10
Congenital brain damage 3
Brain malformation 2
CNS infection sequelae 1
Other 2
Table 2. Laboratory Data the 18 SMID Patients.

From: Evaluation of eGFRs to Calculate Kidney Function in Adults with Severe Motor and Intellectual Disabilities

case sex age height weight BSA CCr CCr-eGFR Cr Cr-eGFR cysC cysC-eGFR β2MG β2MG-eGFR Alb
(y) (cm) (kg) (m2) (ml/m/1.73m2) (mg/dL) (ml/m/1.73m2) (mg/L) (ml/m/1.73m2) (mg/) (ml/m/1.73m2) (g/dL)
1 M 20 158.0 34.4 1.27 154.3 117.9 0.35 258.9 0.64 143.3 0.9 174.7 4.2
2 M 21 160.0 34.4 1.28 186.5 142.5 0.43 203.8 0.77 116.8 1.4 115.6 4.5
3 M 30 142.0 37.8 1.22 143.8 109.9 0.41 193.9 0.84 102.1 1.8 91.9 3.9
4 M 31 151.5 33.9 1.22 100.2 76.6 0.29 280.5 0.94 89.8 1.7 96.8 4.5
5 M 36 155.0 38.2 1.31 107.2 81.9 0.51 144.9 1.12 72.2 2.2 76.9 4.5
6 M 48 151.0 48.1 1.42 109.1 83.4 0.50 136.3 0.76 105.5 1.6 102.3 4.0
7 M 49 150.0 37.4 1.27 122.3 93.5 0.61 109.0 1.03 74.9 1.9 87.6 3.9
8 M 50 148.0 27.9 1.11 83.6 63.9 0.60 110.4 1.14 66.5 2.2 76.9 3.9
9 M 52 145.0 31.9 1.15 50.1 38.3 0.64 101.7 1.09 69.3 2.5 68.8 3.4
10 M 60 186.0 61.2 1.82 90.1 68.8 0.47 136.8 0.97 76.3 2.7 64.3 3.1
11 F 26 156.2 40.0 1.34 127.3 97.3 0.32 195.8 0.56 149.2 0.9 174.7 4.4
12 F 37 148.0 40.5 1.30 126.2 96.4 0.48 113.5 0.79 97.9 1.4 115.6 4.1
13 F 39 129.0 34.7 1.10 81.8 62.5 0.51 104.6 1.15 63.7 3.0 58.8 3.7
14 F 40 141.0 31.3 1.12 221.6 69.3 0.17 345.6 0.67 115.8 1.3 123.8 4.1
15 F 50 164.5 57.5 1.63 70.0 53.5 0.38 134.4 0.87 83.1 2.4 71.2 3.3
16 F 72 143.5 39.5 1.25 105.3 80.5 0.31 151.3 0.76 87.8 2.1 80.1 3.3
17 F 55 148.0 39.8 1.29 105.7 80.7 0.30 169.4 0.81 88.1 1.4 115.6 3.9
18 F 35 140.0 30.4 1.10 255.9 195.5 0.35 163.0 0.53 152.4 1.2 133.3 3.2
Table 3. Comparison of Performance among the Three eGFR Equations, eGFR-Cr, eGFR-cysC, and eGFR-Β2MG, Using eGFR-Ccr as the Gold Standard.

From: Evaluation of eGFRs to Calculate Kidney Function in Adults with Severe Motor and Intellectual Disabilities

ME (mL/min/1.73 m2) (95% CI) RMSE (mL/min/1.73 m2) P30 (%)
eGFR-Cr 74.5 (−12.1 to 192.2) 92.3 16.7
eGFR-cysC 2.3 (−49.1 to 43.1) 25.7 77.8
eGFR-Β2MG 6.5 (−55.1 to 68.7) 33.4 72.2
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