Table 1. Comparison of Patients’ Profiles between TSP and TMP before the Intervention.

From: Real-world Evidence for the Treatment of Rosacea with Sulfur or Metronidazole Preparation in Japanese Patients

Topical treatment
Parameters TSP TMP p-value
Age (years) 46.2 ± 21.3 48.1 ± 11.9 0.469
Sex (number of patients) 0.237
 Male 3 1
 Female 19 24
Type of rosacea (number of patients) 0.861
 ETR 10 12
 PPR 12 13
Results of Demodex exam. (number of patients) 0.632
 Positive 18 20
 Negative 4 4
 Not examined 0 1
IGA score (number of patients) 0.600
 2 5 9
 3 9 9
 4 8 7
VAS score (mean value ± standard deviation)
 Itch 50.2 ± 31.4 37.2 ± 25.7 0.094
 Burning sensation 24.5 ± 28.8 29.1 ± 26.2 0.303
 Flushing 27.1 ± 27.6 28.1 ± 27.5 0.839
 Hypersensitivity 50.4 ± 29.9 54.6 ± 28.9 0.654
IGA score (mean value ± standard deviation) 3.14 ± 0.77 2.92 ± 0.81 0.353
Table 2. Comparison of Outcomes between TSP and TMP.

From: Real-world Evidence for the Treatment of Rosacea with Sulfur or Metronidazole Preparation in Japanese Patients

Topical treatment
Parameters TSP TMP p-value
Results of Demodex exam. (number of patients) 0.212
 Positive 6 8
 Negative 15 12
 Not examined 1 5
Adverse events (number of patients) 0.215
 Absent 13 19
 Present 9 6
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