| High donor LISI (−1.23<) |
Low donor LISI (≤−1.23) |
p-value | |
|---|---|---|---|
| Subject | N = 43 | N = 70 | |
| Recipient factors | |||
| Gender, male | 35 (81.4) | 48 (68.6) | 0.13 |
| Age (years) | 56 [51-62] | 58 [54-65] | 0.08 |
| BMI (kg/m2) | 24.0 [21.7-26.4] | 24.5 [21.6-27.0] | 0.37 |
| GWRW | 0.86 [0.76-1.0] | 0.85 [0.75-1.0] | 0.88 |
| Outside the Milan criteria | 18 (41.9) | 34 (48.6) | 0.48 |
| Outside the Japan criteria | 6 (14.0) | 12 (17.1) | 0.65 |
| MELD score | 12 [8.3-16] | 13 [10.3-18] | 0.29 |
| Cold ischemic time (min) | 90 [66-112] | 78 [51-115] | 0.08 |
| Fibrosis-4 index | 0.66 [0.47-1.12] | 0.89 [0.63-1.14] | 0.10 |
| Recipient LISI | 7.64 [4.47-10.0] | 8.21 [5.10-11.22] | 0.17 |
| NK cell therapy | 10 (23.3) | 32 (45.7) | 0.02 |
| Operation time (min) | 723 [670-785] | 753 [663-844] | 0.17 |
| Bleeding volume (mL) | 2,970 [2,100-4,900] | 3,695 [2,216-5,611] | 0.27 |
| AFP (ng/mL) | 13.4 [5.6-50.9] | 8.1 [5-40.0] | 0.29 |
| DCP (mAU/mL) | 27 [15-94] | 78 [25-519] | <0.01 |
| Timor size (mm) | 20 [14-28] | 20 [12-30] | 0.75 |
| Tumor number | 2 [1-4] | 2 [1-4] | 0.73 |
| Vascular invasion, yes | 11 (25.6) | 12 (17.1) | 0.28 |
| Poorly differentiated, yes | 4 (9.3) | 8 (11.4) | 0.72 |
| Donor factors | |||
| Gender, male | 20 (46.5) | 53 (75.7) | <0.01 |
| Age (years) | 43 [29-54] | 30.5 [27-38] | <0.01 |
| BMI (kg/m2) | 20.7 [19.7-21.9] | 22.9 [20.5-24.5] | <0.01 |
| Donor fibrosis-4 index | 0.86 [0.59-1.16] | 0.54 [0.41-0.75] | <0.01 |
| Donor LISI | 0.70 [−0.53-2.22] | −3.15 [−4.2-2.22] | <0.01 |
| High donor LISI (−1.23<) |
Low donor LISI (≤−1.23) |
p-value | |
|---|---|---|---|
| Subject | N = 27 | N = 27 | |
| Recipient factors | |||
| Gender, male | 21 (77.8) | 19 (70.4) | 0.53 |
| Age (years) | 56 [51-61] | 56 [53-60] | 0.84 |
| BMI (kg/m2) | 23.7 [21.7-26.4] | 23.6 [21.4-27.3] | 0.80 |
| GWRW | 0.84 [0.75-0.90] | 0.85 [0.75-0.99] | 0.42 |
| Outside the Milan criteria | 11 (40.7) | 10 (37.0) | 0.78 |
| Outside the Japan criteria | 4 (14.8) | 3 (11.1) | 0.69 |
| MELD score | 12 [9-17] | 12 [10-14] | 0.81 |
| Cold ischemic time (min) | 89 [57-123] | 92 [70-119] | 0.78 |
| Fibrosis-4 index | 0.69 [0.49-1.12] | 0.85 [0.46-1.02] | 0.82 |
| Recipient LISI | 7.65 [4.67-8.85] | 7.69 [4.19-10.3] | 0.77 |
| NK cell therapy | 8 (29.6) | 8 (29.6) | 1.00 |
| Operation time (min) | 735 [670-797] | 752 [657-815] | 0.57 |
| Bleeding volume (mL) | 2,966 [2,100-5,040] | 3,580 [2,150-4,700] | 0.59 |
| AFP (ng/mL) | 13.4 [5.6-108] | 6.8 [5-40.3] | 0.30 |
| DCP (mAU/mL) | 27 [17-96] | 34 [15-98] | 0.71 |
| Timor size (mm) | 22 [14-28] | 19 [10-25] | 0.28 |
| Tumor number | 2 [1-4] | 2 [1-4] | 0.70 |
| Vascular invasion, yes | 6 (22.2) | 4 (14.8) | 0.48 |
| Poorly differentiated, yes | 2 (7.4) | 2 (7.4) | 1.00 |
| Donor factors | |||
| Gender, male | 11 (40.7) | 22 (81.5) | <0.01 |
| Age (years) | 48 [33-54] | 29 [25-34] | <0.01 |
| BMI (kg/m2) | 20.7 [19.7-21.9] | 22.8 [20.4-24.4] | <0.01 |
| Donor fibrosis-4 index | 0.94 [0.62-1.21] | 0.55 [0.41-0.76] | <0.01 |
| Donor LISI | 0.68 [−0.69-2.12] | −3.16 [−3.99-2.41] | <0.01 |
