Ludwig’s Angina and Mandibular Osteomyelitis after Dental Extraction

Yuki Otsuka, Ko Harada, Yoshito Nishimura, and Fumio Otsuka
Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Corresponding author: Yoshito Nishimura,

DOI: 10.31662/jmaj.2018-0031

Received: September 6, 2018
Accepted: September 26, 2018
Advance Publication: November 12, 2018
Published: March 4, 2019

Cite this article as:
Otsuka Y, Harada K, Nishimura Y, Otsuka F. Ludwig’s Angina and Mandibular Osteomyelitis after Dental Extraction. JMA J. 2019;2(1):87-88.

Key words: Ludwig’s angina, Osteomyelitis, Dental infection, Imaging

A 63-year-old Japanese man was admitted to our hospital owing to dysphagia, hoarseness, and jaw swelling (Figure 1A, B). He had undergone left lower wisdom-tooth extraction 3-weeks prior to admission. Contrast-enhanced computed tomography (CT) demonstrated submandibular cellulitis and abscess formation (Figure 1C). Magnetic resonance imaging (MRI) showed a low signal intensity lesion in the left mandible on the T1-weighted image (Figure 1D). These findings were consistent with Ludwig’s angina complicated with abscess and submandibular osteomyelitis. Blood cultures obtained on the day of admission showed negative results. Intravenous ampicillin/sulbactam was administered, and the symptoms improved. Ludwig’s angina, a severe cellulitis in submandibular space, is most commonly caused by a dental infection, especially in the second or third molar (1). Submandibular osteomyelitis is a severe complication after dental therapy; however, its diagnosis is often neglected because of its indeterminate symptoms (2). Furthermore, owing to the low sensitivity of CT in the diagnosis of osteomyelitis, MRI is essential when osteomyelitis is suspected.

Figure 1. (A), (B) Physical examination revealed swelling and redness in the jaw. (C) Contrast-enhanced computed tomography (CT) demonstrated cellulitis in the patient’s jaw (arrowheads) and formation of an abscess (20-mm diameter) in front of the hyoid bone (arrow). (D) Magnetic resonance imaging (MRI) showed a low signal intensity lesion in the body of the left mandible on the T1-weighted image (arrows).

Article Information

Conflicts of Interest


Author Contributions

YO wrote the manuscript. KH was an inpatient attending physician and edited the manuscript. YN edited the manuscript. FO supervised all the procedures.

Ethical Statement

Informed consent was obtained from the patient.


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