Figure 1. a. Bone scintigraphy before treatment. Multiple foci of increased tracer uptake were observed in the sternum (red arrow), costochondral junction (red arrowheads), and knee joints (blue arrows). These are known as the “tie sign,” “rachitic rosary sign,” and “accumulation in the knees,” respectively. b. Bone scintigraphy after treatment. The multiple uptake sites have almost disappeared.

From: Scintigraphic Findings in FGF23-related Hypophosphatemic Osteomalacia