| Age (years), mean (SD) |
71 (17) |
| Male, n (%) |
183,928 (55) |
| Charlson comorbidity index, mean (SD) |
1.4 (1.9) |
| Planned or emergency admission, n (%) |
|
| Planned admission |
172,754 (51) |
| Emergency admission |
164,378 (49) |
| Intensive care unit admission, n (%) |
89,316 (26) |
| High-care unit admission, n (%) |
55,066 (16) |
| Surgery with general anesthesia, n (%) |
88,523 (26) |
| Use of antibiotics, n (%) |
314,033 (93) |
| Annual hospital volume (patients per year), mean (SD) |
76 (52) |
| Underlying disorders, n (%) |
|
| Marked bleeding type of DIC |
|
| Leukemia |
31,059 (9) |
| Trauma |
16,844 (5) |
| Obstetric diseases |
16,742 (5) |
| Aortic diseases |
9,721 (3) |
| Organ failure type of DIC |
|
| Sepsis |
140,538 (42) |
| Lung |
37,847 (11) |
| Abdomen |
41,224 (12) |
| Urinary tract |
26,733 (8) |
| Central nervous system |
3,274 (1) |
| Skin and soft tissues |
4,882 (2) |
| Cardiovascular system |
6,429 (2) |
| Other infections |
38,090 (11) |
| Pancreatitis |
9,052 (3) |
| Asymptomatic type of DIC |
|
| Solid cancer |
104,323 (31) |
| Esophagus |
3,749 (1) |
| Stomach |
17,911 (5) |
| Colon |
19,816 (6) |
| Liver |
9,578 (3) |
| Bile duct/gallbladder |
10,188 (3) |
| Pancreas |
10,707 (3) |
| Lung |
10,816 (3) |
| Gynecological |
4,874 (1) |
| Urological |
10,981 (3) |
| Breast |
2,575 (1) |
| Other solid cancers |
12,503 (4) |
| Miscellaneous |
8,853 (3) |
| Anticoagulants used for DIC, n (%) |
|
| Antithrombin |
85,488 (25) |
| Recombinant thrombomodulin |
122,224 (36) |
| Serine protease inhibitors |
125,344 (37) |
| Heparin |
102,048 (30) |
| Antifibrinolytics used for DIC, n (%) |
|
| Tranexamic acid |
47,408 (14) |
| Blood components used for DIC, n (%) |
|
| Fresh frozen plasma |
87,098 (26) |
| Platelets |
82,959 (25) |
| Organ failure score, mean (SD) |
2.0 (1.0) |
| Major bleeding events, n (%) |
33,454 (10) |
| Outcomes |
|
| In-hospital mortality, n (%) |
125,933 (37) |
| Length of stay (days), mean (SD) |
41 (83) |
| Total hospitalization costs (thousands of USD), mean (SD) |
25 (31) |
